Adipositas - Ursachen, Folgeerkrankungen, Therapie, Table of Contents Adipositas - Ursachen, Folgeerkrankungen, Therapie 2012; 06(01): 51DOI: 10.1055/s-0037-1618774 Serie Diabetes Schattauer GmbH Adipositas, Diabetes und Krebs Authors S. Herzig A. Vegiopoulos Recommend Article Abstract Buy Article(opens in new window) Full Text References Literatur 1 Barone BB, Yeh HC, Snyder CF, Peairs KS, Stein KB, Derr RL. et al. Long-term all-cause mortality in cancer patients with preexisting diabetes mellitus: a systematic review and meta-analysis. JAMA 2008; 300: 2754-2764. 2 Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 2003; 348: 1625-1638. 3 Calle EE, Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer 2004; 04: 579-591. 4 Carmichael AR. Obesity and prognosis of breast cancer. Obes Rev 2006; 07: 333-340. 5 El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-2576. 6 Giovannucci E, Harlan DM, Archer MC, Bergenstal RM, Gapstur SM, Habel LA. et al. Diabetes and cancer: a consensus report. Diabetes Care 2010; 33: 1674-1685. 7 Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010; 140: 883-899. 8 Grote VA, Becker S, Kaaks R. Diabetes mellitus type 2 – an independent risk factor for cancer?. Exp Clin Endocrinol Diabetes 2010; 118: 4-8. 9 Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995; 95: 2409-2415. 10 Hursting SD, Lavigne JA, Berrigan D, Perkins SN, Barrett JC. Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. Annu Rev Med 2003; 54: 131-152. 11 IACR/WHO. IARC Handbooks of Cancer Prevention: Weight Control and Physical Activity. Lyon, France: International Agency for Research on Cancer; 2002 12 Jones RA, Campbell CI, Gunther EJ, Chodosh LA, Petrik JJ, Khokha R. et al. Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation. Oncogene 2007; 26: 1636-1644. 13 Kaaks R, Lukanova A, Kurzer MS. Obesity, endogenous hormones, and endometrial cancer risk: a synthetic review. Cancer Epidemiol Biomarkers Prev 2002; 11: 1531-1543. 14 Kern PA, Ranganathan S, Li C, Wood L, Ranganathan G. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab 2001; 280: E745-751. 15 Key TJ, Appleby PN, Reeves GK, Roddam A, Dorgan JF, Longcope C. et al. Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J Natl Cancer Inst 2003; 95: 1218-1226. 16 Parekh N, Okada T, Lu-Yao GL. Obesity, insulin resistance, and cancer prognosis: implications for practice for providing care among cancer survivors. J Am Diet Assoc 2009; 109: 1346-1353. 17 Parekh S, Anania FA. Abnormal lipid and glucose metabolism in obesity: implications for nonalcoholic fatty liver disease. Gastroenterology 2007; 132: 2191-2207. 18 Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG. et al. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell 2010; 140: 197-208. 19 Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer 2008; 08: 915-928. 20 Pollak M, Russell-Jones D. Insulin analogues and cancer risk: cause for concern or cause celebre?. Int J Clin Pract 2010; 64: 628-636. 21 Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 2008; 371: 569-578. 22 Sharma D, Wang J, Fu PP, Sharma S, Nagalingam A, Mells J. et al. Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis. Hepatology 2010; 52: 1713-1722. 23 Shoelson SE, Herrero L, Naaz A. Obesity, inflammation, and insulin resistance. Gastroenterology 2007; 132: 2169-2180. 24 Van der Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009; 324: 1029-1033. 25 WCRF/AICR. Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective. Washington, DC: AICR; 2007 26 Wu Y, Brodt P, Sun H, Mejia W, Novosyadlyy R, Nunez N. et al. Insulin-like growth factor-I regulates the liver microenvironment in obese mice and promotes liver metastasis. Cancer Res 2010; 70: 57-67.
