Some Comparative Studies Using 99mTc and 131I in Thyroid Scanning

T. Górowski; O. A. Chomicki

doi:10.1055/s-0038-1624975

Nuklearmedizin - NuclearMedicine, Table of Contents

Nuklearmedizin 1976; 15(06): 268-272
DOI: 10.1055/s-0038-1624975

Originalarbeiten — Original Articles

Schattauer GmbH

Some Comparative Studies Using ^99mTc and ¹³¹I in Thyroid Scanning

Authors

T. Górowski

¹From the Department of Thyroid Diseases, Endocrinology Clinic, Postgraduate Medical School (Head: Prof. W. Hartwig), Warsaw
O. A. Chomicki

¹From the Department of Thyroid Diseases, Endocrinology Clinic, Postgraduate Medical School (Head: Prof. W. Hartwig), Warsaw

Abstract

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Summary

By comparing thyroid scans made with ^99mTc and ¹³¹I in 40 euthyroid goiter patients large discrepancies were found in 20% of all cases. For example, “warm” nodules on ^99mTc scans were found to be “cold” on ¹³¹I scans, or a “cold” nodule on a ^99mTc scan was observed as a “warm” one on a ¹³¹I scan. The above discrepancies seem to result from the differences in the metabolism of the two radioisotopes in the thyroid and those in the time which elapsed between the administration of the radioisotope and the execution of the scan.

Generally speaking ^99mTc thyroid scintigraphy should not be recommended as a routine technique in adults, its usefulness being limited to the cases in which ¹³¹I scans were found to be illegible. “Cold” nodules on ^99mTc scans should also be reexamined after T₃ stimulation.

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References

References
1 Atkins H. L, Richards P. Assessement of thyroid function and anatomy with technetium-99m as pertech-nate. J. Nucl. Med 1968; 7: 9.
2 Cheguillaume J. et al. Intérĕt de l’emploi du tech-netium-99m dans l’esploration thyroïdienne. Arch. Med. Angers, suppl. au Nr. 1. 1967
3 Górowski T, Ruka W, Czech W, Chomicki O. A. The effect of preoperative thyroid lymphography on the results of non-toxic goiter surgery and some thyroid function tests. Pol. Tyg. Lek. (in Polish, in print).
4 Hays M. T, Wesselessky B. Simultaneous measurement of thyroid trapping (^99mTcO^– ₄) and (¹³¹I^–): Clinical and experimental studies. J. Nucl. Med 1973; 14: 785.
5 Itch K. et al. Comparison of thyroid scanning with ^99mTc-pertechnetate and ¹³¹I-iodide, Radioisotopes (Japan). 1975; 7: 24.
6 Johnson P. M. Clinical use of thyroid scan; in. Werner S. C, Ingbar S. H. in The Thyroid. 3rd ed. Harper and Row; New York: 217 1971
7 Krishnamurthy G. T. et al. Comparison of (99m) technetium pertechnetate and radioiodine (¹³¹I). Nucl. Med 1973; 12: 97.
8 Rohacek J. Schilddrüsenuntersuchung mit den Radionukliden ¹³¹J and Tc^99m . Radiobiol., Radiother. (Berlin) 1973; 14: 383.
9 Sanders T. P, Kuhl D. E. Technetium Pertechnetate as a Thyroid Scanning Agent. Radiology 1968; 23: 91.
10 Schall G. L. et al. Differential uptake of ¹²⁵J and (99m) TcO₄ in a histologically unusual metastatic carcinoma. J. Surg. Oncol 1973; 5: 235.
11 Steinberg M. et al. Uptake of technetium 99m pertechnetate in a primary thyroid carcinoma: need for caution in evaluating nodules. J. Clin. Endocr 1970; 31: 81.
12 Wagner Jr. H. N. (ed.) in Principles of Nuclear Medicine; Saunders, Philadelphia: 1968
13 Wojciechowski J. et al. Scintigraphic studies of thyroid nodules after the administration of Tc-99m and I-131. Endokrynologia Polska (in Polish) 1975; 26: 176.