Endoscopy 2018; 50(04): S15
DOI: 10.1055/s-0038-1637068
ESGE Days 2018 oral presentations
20.04.2018 – Colon: Improving detection
Georg Thieme Verlag KG Stuttgart · New York

LINKED COLOR IMAGING REDUCES THE MISS RATE OF NEOPLASTIC LESIONS IN THE RIGHT COLON: A RANDOMIZED TANDEM COLONOSCOPY STUDY

S Paggi
1   Ospedale Valduce, Gastroenterology, Como, Italy
,
G Mogavero
2   University of Palermo, Gastroenterology Unit, Biomedical Department of Internal and Specialized Medicine (Di.Bi.M.I.S), Palermo, Italy
,
A Amato
1   Ospedale Valduce, Gastroenterology, Como, Italy
,
A Andrealli
1   Ospedale Valduce, Gastroenterology, Como, Italy
,
G Imperiali
1   Ospedale Valduce, Gastroenterology, Como, Italy
,
N Lenoci
1   Ospedale Valduce, Gastroenterology, Como, Italy
,
G Mandelli
1   Ospedale Valduce, Gastroenterology, Como, Italy
,
E Rondonotti
1   Ospedale Valduce, Gastroenterology, Como, Italy
,
N Terreni
1   Ospedale Valduce, Gastroenterology, Como, Italy
,
G Spinzi
1   Ospedale Valduce, Gastroenterology, Como, Italy
,
F Radaelli
1   Ospedale Valduce, Gastroenterology, Como, Italy
› Author Affiliations
Further Information

Publication History

Publication Date:
27 March 2018 (online)

Also available at
 

Aims:

To evaluate whether Linked Color Imaging (LCI), a new imaging system integrated in the ELUXEO 700-series videoendoscopes (Fujifilm Co., Tokyo), can improve the detection of adenomas and sessile serrated adenomas/polyps (SSAPs) in the right colon when compared with high-definition white light (HD-WL) colonoscopy.

Methods:

Consecutive patients undergoing colonoscopy for screening, surveillance or diagnostic assessment were recruited. At cecal intubation, patients with adequalte colon cleansing were randomized (1:1) to tandem colonoscopy in the right colon with LCI followed by WLI (LCI-WLI group) or WLI followed by LCI (WLI-LCI group). Lesions detected on first-pass and second-pass examination were used for detection and miss-rates, respectively. The primary outcome were the right colon adenoma miss-rate, defined as the number of adenomas identified during the second right colon inspection divided by overall number of adenomas identified during the first and second right colon inspections. Examinations were performed with Fuji videocolonscopes series-700 (EC-760R, EC-760ZP).

Results:

A total of 600 patients were enrolled. Of them, 142 had at least one adenoma detected in the right colon, acoounting for an right-colon adenoma detection (rc-ADR) rate of 23.6%. At per patient analysis, in the LCI-WLI and in the WLI_LCI group the rc-ADR were 22,6% (68/300 patients) and 24,6% (74/300) (p = NS). In the LCI-WLI group at least one adenoma was identified in the second pass (WLI) in 12 of 68 patients (17,6%) and in the WLI-LCI group in 30 of 74 patients (40,5%). (p = 0.005). At per-polyp analysis, a total of 211 and 18 adenomas and SSAPs were detected, respectively. The double inspection of right colon in the LCI-WLI and WLI-LCI groups resulted in a 11,8% (13/110) and 30,6% (34/111) adenoma miss-rate, respectively (p < 0,001). Corresponding figures for SSAPs were 33,3% (2/6) and 50% (6/12), respectively (p = 0,502)

Conclusions:

Present study suggests that LCI can reduce the miss-rate of neoplastic lesions in the right colon. (NCT03279783)