Endoscopy 2018; 50(04): S144
DOI: 10.1055/s-0038-1637465
ESGE Days 2018 ePosters
Georg Thieme Verlag KG Stuttgart · New York

MUCOSAL INCISION DEEP BIOPSY IS USEFUL AND SAFE DIAGNOSTIC TECHNIQUE FOR SUBEPITHELIAL TUMORS

JS Moon
1   Seoul Paik Hospital, Inje University College of Medicine, Internal Medicine, Seoul, Korea, Republic of
,
KH Ko
1   Seoul Paik Hospital, Inje University College of Medicine, Internal Medicine, Seoul, Korea, Republic of
,
YM Woo
1   Seoul Paik Hospital, Inje University College of Medicine, Internal Medicine, Seoul, Korea, Republic of
,
JY Kim
1   Seoul Paik Hospital, Inje University College of Medicine, Internal Medicine, Seoul, Korea, Republic of
,
TY Park
1   Seoul Paik Hospital, Inje University College of Medicine, Internal Medicine, Seoul, Korea, Republic of
,
SH Ryu
1   Seoul Paik Hospital, Inje University College of Medicine, Internal Medicine, Seoul, Korea, Republic of
,
YS Kim
1   Seoul Paik Hospital, Inje University College of Medicine, Internal Medicine, Seoul, Korea, Republic of
,
SY Seol
2   Inje University Busan Paik Hospital, Inje University College of Medicine, Department of Internal Medicine, Busan, Korea, Republic of
› Author Affiliations
Further Information

Publication History

Publication Date:
27 March 2018 (online)

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Aims:

Acquiring sufficient tissue is important for the definite diagnosis of subepithelial tumors (SETs). Better tissue sampling techniques are needed to improve pathological diagnosis. The aim of this study was to evaluate the usefulness and safety of mucosal incision deep biopsy.

Methods:

This study enrolled 10 patients (M:F = 4:6) who underwent mucosal incision deep biopsy of gastric SETs at Seoul Paik Hospital. The medical records of patients were reviewed retrospectively. We examined tumor size, location, origin of layer, pathological diagnosis, treatment and procedure-related complications.

Results:

The median size of the SETs was 19.7 mm. The locations of tumors were 4 cases in antrum, 3 cases in body, 2 cases in cardia, and 1 case in fundus. By Endoscopic ultrasound (EUS) imaging, all tumors were originated from proper muscle (PM) layer. The diagnostic yield of mucosal incision deep biopsy was 100%, so that pathological diagnosis of subepithelial tumor could be obtained in all the cases (GIST, n= 7; leiomyoma, n= 2; and ectopic pancreas, n= 1). However, two tissue samples were insufficient to measure the grade of GIST. There were no major procedure-related complications, but just in one case micro-perforation was found after this procedure. In 2 out of the 7 patients with GIST underwent surgical resection because they had relatively high malignancy potential in EUS and tissue feature.

Conclusions:

The mucosal incision deep biopsy technique can be a useful and relatively safe diagnostic modality for the diagnosis of gastric SETs and for selection of the appropriate treatment.