Endoscopy 2018; 50(04): S152-S153
DOI: 10.1055/s-0038-1637493
ESGE Days 2018 ePosters
Georg Thieme Verlag KG Stuttgart · New York

EFFECT OF INTRAGASTRIC BALLOON-INDUCED WEIGHT LOSS ON BODY COMPOSITION, FATTY LIVER AND CO-MORBIDITIES IN EGYPTIAN MIDDLE-AGED OBESE FEMALES: A SIX-MONTH FOLLOW-UP STUDY

A Shamseya
1   University of Alexandria, Internal Medicine, Alexandria, Egypt
,
M Shamseya
2   University of Alexandria, Department of Clinical and Experimental Internal Medicine, Medical Research Institute, Alexandria, Egypt
,
M Madkour
2   University of Alexandria, Department of Clinical and Experimental Internal Medicine, Medical Research Institute, Alexandria, Egypt
,
K Aly Abdelaaty
3   Faculty of Medicine, University of Alexandria, Internal Medicine, Alexandria, Egypt
› Author Affiliations
Further Information

Publication History

Publication Date:
27 March 2018 (online)

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Aims:

A group of obese middle-aged Egyptian female subjects treated with intragastric balloon to induce weight loss was prospectively followed up and reported its effect on their anthropometric measurements, body composition, fatty liver and co-morbidities.

Methods:

47 middle-aged female patients were enrolled for BIB insertion. Inclusion criteria were mainly based on the BMI (≥30.0 kg/m2) and on associated co-morbidities. Apart from physical and anthropometric evaluation, body composition analysis was performed using bioelectrical impedance analyzer (BIA) to estimate fat mass (FM), body fat percentage (BF %) and fat free mass (FFM).

Results:

Overall, BIB insertion significantly reduced weight from a mean value of 96.82 ± 14.18 kg at baseline to 83.45 ± 12.03 kg after 6 months (p < 0.001). The mean value for the amount of weight lost at endpoint was 13.36 ± 3.29 kg, while the mean value for BMI lost at the time of BIB removal was 5.12 ± 1.20 kg/m2, which was a significant reduction compared to baseline values (p < 0.001). Body fat mass and body fat percentage by BIA were significantly reduced (p < 0.001). However, there was also a significant decline in fat free mass (< 0.001). Significant favorable changes in the biochemical markers of metabolic syndrome, HOMA-IR index and liver profile also occurred. 4.6% of patients showed resolution, while 31.8% showed improvement in the features of metabolic syndrome.

Conclusions:

This study provides anthropometric, biochemical, and body composition evidence on significant improvement of metabolic syndrome, obesity associated co-morbidities and fatty liver after weight loss induced by minimally-invasive and relatively safe technique.