Endoscopy 2018; 50(04): S168-S169
DOI: 10.1055/s-0038-1637547
ESGE Days 2018 ePosters
Georg Thieme Verlag KG Stuttgart · New York

POPULATION-BASED STUDY. SCREENING FOR COLORECTAL CANCER. DIFFERENCES BETWEEN MALES AND FEMALES. RESULTS IN 73545 SUBJECTS

G Hontoria Bautista
1   Universitary Hospital of Burgos, Burgos, Spain
,
MA Jimenez Moreno
1   Universitary Hospital of Burgos, Burgos, Spain
,
R Pereda Garcia
1   Universitary Hospital of Burgos, Burgos, Spain
,
J Sanz Sanchez
1   Universitary Hospital of Burgos, Burgos, Spain
,
B Bernad Cabredo
1   Universitary Hospital of Burgos, Burgos, Spain
,
A Moncada Urdaneta
1   Universitary Hospital of Burgos, Burgos, Spain
,
E Badia Aranda
1   Universitary Hospital of Burgos, Burgos, Spain
,
B Sicilia Aladren
1   Universitary Hospital of Burgos, Burgos, Spain
,
S Garcia Moran
1   Universitary Hospital of Burgos, Burgos, Spain
,
JL Martin Lorente
1   Universitary Hospital of Burgos, Burgos, Spain
,
F Saez-Royuela Gonzalo
1   Universitary Hospital of Burgos, Burgos, Spain
› Author Affiliations
Further Information

Publication History

Publication Date:
27 March 2018 (online)

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Aims:

To describe the findings and the differences in neoplastic findings between sexes in the asymptomatic participants.

Methods:

Screening programme for CRC was introduced in our hospital in october 2014. We collected data until August 2017. Men and women between 50 and 69 years old were invited to undergo a Faecal Occult Blood Test (FOBT). Those who obtained a positive result were offered to perform a colonoscopy.

Results:

In total, 73,545 subjects were invited to take part in the program. Of these, 25414 provided a faecal sample resulting in a 34.6% participation rate. FOBT was positive in 2,501 individuals (7.9%) and 1,815 (72.6%) of them underwent a colonoscopy, 83 subjects were excluded. Of those 1815, colonoscopies were negative or had non neoplasic findings in 282 (25.1%) males and 329 (47,6%) females. We detected low-risk adenomas (LRA) in 217 (19.3%) males and in 153 (19.3%) females, p = 0.14; medium-risk adenoma (MRA) in 257 (22.9%) males and 97 (14%) females, p < 0,0001; and high-risk adenomas (HRA) in 256 (22.7%) males and 73 (10.6%) females, p < 0,0001. Adenoma detection rate (ADR) resulted in 66.3%.151 invasive CRC were found (10% of males and 5.7% of females). The probability of being diagnosed of CRC was higer in males (RR 1.77, 95% IC 1.24 – 2.51; p = 0.0015).

Conclusions:

Participation rate of the screening programme in our hospital is very low, remaining below 45%, established as the acceptable rate in European Guidelines. On the other hand, colonoscopy acceptance rate was 72,6%. However, there are an unknown percentage of people, who decide to perform FOBT and/or colonoscopies in private centres.

FOBT positivity rate was 7.9%, slightly higher than in the rest of Spain (6.8%).

In 58% of participants neoplasic adenomas were resected, avoiding their progression to advanced neoplasia. CRC, HRA and MRA were more frequent in males with similar rates described in bibliography.