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DOI: 10.1055/s-0038-1637609
EVALUATION OF ENDOSCOPIC ULTRASOUND-GUIDED FINE NEEDLE ASPIRATION AND BIOPSY WITH A 19-GAUGE PUNCTURE FORCEPS FOR THE DIAGNOSIS OF PANCREATIC MASSES
Publication History
Publication Date:
27 March 2018 (online)
Aims:
Pancreatic masses include large group of surgical pancreatic diseases. A large-caliber needle such as a 19-gauge puncture forceps may help overcome the limitations of a fine needle aspiration by acquiring a larger amount of tissue sample. However, there has been no study for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) and endoscopic ultrasound-guided fine needle biopsy with a 19-gauge puncture forceps (EUS-FNB).
Aim of study: to compare results endoscopic ultrasound-guided fine needle aspiration and biopsy with a 19-gauge puncture forceps for the diagnosis of pancreatic masses.
Methods:
From March 2016 to September 2017, a total of 30 patients with solid and cystic pancreatic mass were included. Endoscopic ultrasound-guided fine needle aspiration and biopsy with a 19-gauge puncture forceps were performed using the standard technique without an on-site cytopathologist.
Results:
The diagnostic accuracy was significantly higher in EUS-FNA group (84,2 – 100% vs. 38,17 – 75,17%, P = 0.01). Foils negative results higher in the 19-gauge forceps group (6,67% vs. 43,33%, P = 0.01). Sensitivity of EUS-FNA was significantly higher than in a 19-gauge forceps group (84,2 – 100% vs. 38,17 – 75,17%, P = 0.01). The diagnostic accuracy by quality of diagnostic material, value of histological examination was not significantly different (FNA: 84,02 – 100%; 5,07 – 34,93% and FNB: 89,96 – 100%; 21,71 – 58,29%). The diagnostic accuracy by value of cytological examination and immunohistochemistry was significantly higher in EUS-FNA group (84,02 – 100% and 45,34 – 81,33% vs. 24,83 – 61,83% and 5,07 – 34,93%, p ≤0.01). However, frequency of bleeding was higher in EUS-FNB group (0% vs. 7,54% – 39,12%).
Conclusions:
EUS-FNA may be a valuable method for the diagnosis of pancreatic masses when an on-site cytopathologist is not available.