Endoscopy 2018; 50(04): S201
DOI: 10.1055/s-0038-1637659
ESGE Days 2018 ePosters
Georg Thieme Verlag KG Stuttgart · New York

RISK FACTORS FOR COMPLICATIONS RELATED TO THERAPEUTIC ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY (ERCP): AN ANALYSIS OF 505 CASES

K Agar
1   Med Taher Maamouri Hospital, Gastro-Enterology, Nabeul, Tunisia
,
M Medhioub
1   Med Taher Maamouri Hospital, Gastro-Enterology, Nabeul, Tunisia
,
S Jardak
1   Med Taher Maamouri Hospital, Gastro-Enterology, Nabeul, Tunisia
,
L Hamzaoui
1   Med Taher Maamouri Hospital, Gastro-Enterology, Nabeul, Tunisia
,
A Khsiba
1   Med Taher Maamouri Hospital, Gastro-Enterology, Nabeul, Tunisia
,
M Msaddek Azouz
1   Med Taher Maamouri Hospital, Gastro-Enterology, Nabeul, Tunisia
› Author Affiliations
Further Information

Publication History

Publication Date:
27 March 2018 (online)

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Aims:

Endoscopic retrograde cholangiopancreatography (ERCP) is an effective therapy for pancreatobiliary disease with less morbidity compared to surgery.

The aim of this study is to evaluate patient and procedure-related risk factors for ERCP complications.

Methods:

Retrospective descriptive study, including 505 patients who underwent therapeutic ERCPs in our endoscopy unit between January 2006 and August 2017. ERCPs done for palliative therapy for pancreato-biliary cancer were excluded. Risk factors for post-procedure complications were investigated by univariate and multivariate analysis.

Results:

Five hundred and five patients were enrolled, with a mean age of 60.3 years (13 – 98). Principle indications for ERCP were: Residual stones of common bile duct in 41% of cases (n = 211), gallstones with or without biliary complications (Pancreatitis, Angiocholitis) in 32% of cases (n = 164), biliary complications of liver hydatid cysts in 45 cases (9%).

Fifty-one patients (10%) suffered from post-ERCP complications: Acute pancreatitis was seen in 30 patients (6%), cholangitis in 2% of patients (n = 10), hemorrhage in 1.6% of patients (n = 8) and perforation in 3 patients. History of acute pancreatitis was significantly more frequent in patients with post-ERCP complications (p = 0.02). Young age (< 45 years), female gender, history of diabetes mellitus, stent placement and opacification of main pancreatic duct were not found to be risk factors for post-ERCP pancreatitis and overall complications. In univariate analysis, post-endoscopic sphincterotomy (ES) hemorrhage was significantly seen in patients using antiplatelet or anticoagulation drugs (p = 0.03). In multivariate analysis, no independent risk factor was found for post-ES hemorrhage. History of acute pancreatitis, large transpancreatic sphincterotomy, and age > 70 years old were independent risk factors for overall complications and post-ERCP pancreatitis.

Conclusions:

Independent risk factors for post-ERCP complications were: Age > 70 years, history of acute pancreatitis and large transpancreatic sphincterotomy.