Yearbook of Medical Informatics, Inhaltsverzeichnis Yearb Med Inform 2003; 12(01): 621-624DOI: 10.1055/s-0038-1638167 Synopsis Georg Thieme Verlag KG StuttgartComputational approach towards challenges in the post-genomic era Authors Institutsangaben H. Tanaka 1 Department of Bioinformatics Medical Research Institutes Tokyo Medical and Dental University Japan Artikel empfehlen Abstract Volltext Referenzen References 1 International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 2001; 409: 860-921. 2 Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG. et al. The sequence of the human genome. Science 2001; 291: 1304-51. 3 Koonin EV. The emerging paradigm and open problems in comparative genomics. Bioinfomatics 1999; 15 (04) 265-6. 4 Hutchison CA, Peterson SN, Gill SR, Cline RT, White O, Fraser CM. et al. Global transposon mutagenesis and a minimal mycoplasma genome. Science 1999; 286: 2165-9. 5 Koonin EV, Mushegian AR. Complete genome sequences of cellular life forms. Curr opin genet dev 1996; 6 (06) 757-62. 6 Koonin EV, Aravind L, Kondrashov AS. The impact of comparative genomics on our understanding of evolution. Cell 2000; 101 (06) 573-6. 7 Quackenbush J. Computational analysis of microarray data. Nat Rev Genet 2001; Jun 2 (06) 418-27. 8 Raychaudhuri S, Sutpin PD, Chang JT, Altman RB. Basic micro array analysis:grouping and feature reduction. Trends Biotechnol 2001; 19 (05) 189-93. 9 Liang S, Fuhrman S, Somogyi R. REVEAL,a general reverse engineering algorithm for inference of genetic network architectures. Pac Symp Biocomput 1998; 18: 30.. 10 D’haeseleer P, Liang S, Somogyi R. From co-expression clustering to reverse engineering. Bioinfomatics 2000; 16 (08) 707-26. 11 Kitano H. Systems biology: a brief overview. Science 2002; 295: 1662-4. 12 Fell D, Snell K. editors Understanding the Control of Metabolism. Portland Press; 1997 13 Tomita M. Whole cell simulation: a grand challenge of 21st century. Trends Biotechnol 2001; 19 (06) 205-10. 14 Kauffman S. Origins of Life. Oxford: 1994 15 Babarasi A. Linked. Perseus. 2002 16 Watts D. Small Worlds. Princeton. 1999 17 Jeong H, Tombor B, Albert R, Oltavi ZN, Barabasi AL. The large-scale organization of metabolic networks. Nature 2000; 407 6804 651-4. 18 Jeong H, Mason SP, Barabasi AL, Oltavi ZN. Centrality and lethality of protein networks. Nature 2001; 411 6833 41-2.