Autologous fat injection for treatment of periprosthetic leakage Experience in 10 patients

Introduction:

Approximately 15% of all patients with voice prostheses develop periprosthetic leakage with aspiration within 1 – 4 years after the placement of a voice prosthesis. The therapeutical algorithm for the management also includes augentation technics. The injection of fat, Bioplastique, collagen, hyaluronic acid, cymetra and granulocyte-macrophage colony-stimulating factor (GMCSF) or granulocyte colony-stimulating factor (GCSF) has been reported. The number of patients who were treated by injections ranges between one and ten in the literature.

Methodes:

10 patients with fistula enlargement from 9 mm to 12 mm were treated with autologous fat injection between January and October 2017.

Results:

The mean quantity of injected fat was 1.8 ml. 8 of 10 patients could be provided with a new voice prothesis directly after fat augmention. In one patient an additional silicon washer was needed (Xtraflange). One patient could not be sealed sufficiently.

Conclusion:

Autologous fat augmentation is a simple procedure with a low complication rate, with allows the sufficient treatment of enlarged voice fistula up to 12 mm. We observed no foreign body or rejection reactions. In four Patients a stable therapy success was documented.

Publication History

Publication Date:
18 April 2018 (online)