Studies on a Subcellular System for Vitamin K- Dependent Carboxylation

R Wallin; H Prydz

doi:10.1055/s-0038-1646805

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1979; 41(03): 529-536
DOI: 10.1055/s-0038-1646805

Original Articles

Schattauer GmbH Stuttgart

Studies on a Subcellular System for Vitamin K- Dependent Carboxylation

Authors

R Wallin

The Institute of Medical Biology, University of Tromso, Tromso, Norway
H Prydz

The Institute of Medical Biology, University of Tromso, Tromso, Norway

Abstract

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Summary

The subcellular localization of acarboxyprothrombin and the vitamin K-dependent carboxylation system has been studied using livers from vitamin K-deficient rats and found to be mainly in the membranes of the rough microsomal fraction. Bovine acarboxyprothrombin or fragment 1 thereof were inactive as substrates in the rat carboxylating sytem.

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References

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