Human Platelets Contain mRNA Transcripts for Platelet Factor 4 and Actin

Jane Sottile; Deane F Mosher; Jan Fullenweider; James N George

doi:10.1055/s-0038-1647125

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 1989; 62(04): 1100-1102
DOI: 10.1055/s-0038-1647125

Original Article

Platelets

Schattauer GmbH Stuttgart

Human Platelets Contain mRNA Transcripts for Platelet Factor 4 and Actin

Autoren

Jane Sottile

The Departments of Physiological Chemistry and Medicine, University of Wisconsin, Madison, WI, USA
Deane F Mosher

The Departments of Physiological Chemistry and Medicine, University of Wisconsin, Madison, WI, USA
Jan Fullenweider

The Departments of Physiological Chemistry and Medicine, University of Wisconsin, Madison, WI, USA
James N George

The Departments of Physiological Chemistry and Medicine, University of Wisconsin, Madison, WI, USA

Abstract

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Summary

RNAs from a number of cells, including platelets, were analyzed by Northern blotting for the presence of transcripts to four platelet proteins - actin, thrombospondin, fibronectin, and platelet factor 4. RNA from platelets contains considerable amounts of mRNA for platelet factor 4, easily detectable mRNA for actin, and traces of mRNA for thrombospondin. mRNA for platelet factor 4 was not detected in human lymphocytes or in any of 5 human cell lines.

Keywords

Platelet mRNA - Platelet factor 4 - Thrombospondin

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Referenzen

References
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