Thromb Haemost 1975; 33(01): 130-131
DOI: 10.1055/s-0038-1647825
Letter to the Editor
Schattauer GmbH

Comparative Evaluation of a Platelet Serotonin Assay Utilizing Ortho-Phthaldialdehyde for Fluorophore Production

Jonathan L Costa
1   Laboratory of Clinical Science Section on Clinical Neuropharmacology NIMH Bethesda, Md. 20014
,
J. Steven Richardson
1   Laboratory of Clinical Science Section on Clinical Neuropharmacology NIMH Bethesda, Md. 20014
,
Dennis L Murphy
1   Laboratory of Clinical Science Section on Clinical Neuropharmacology NIMH Bethesda, Md. 20014
› Author Affiliations
Further Information

Publication History

Publication Date:
02 July 2018 (online)

 

 
  • References

  • 1 Bogdanski B. F, Pletscher A, Brodie B. B, Udenfriend S. Identification and assay of serotonin in brain. Journal of Pharmacology and Experimental Therapeutics 1956; 117: 82
  • 2 Costa J. L, Reese T. S, Murphy D. L. Serotonin storage in platelets: estimation of storage-packet size. Science 1974; 183: 537
  • 3 Crosti P. F, Lucchelli P. E. An easy method to determine the serotonin content of human platelets. Journal of Clinical Pathology 1962; 15: 191
  • 4 Drummond A. H, Gordon J. L. Rapid sensitive microassay for platelet 5HT. Thrombosis et Diathesis Haemorrhagica 1974; 31: 366
  • 5 Komesu N. N, Thompson J. H. Optimal concentration of orthophthaldialdehyde for the fluorometric measurement of serotonin. European Journal of Pharmacology 1971; 16: 248
  • 6 Saavedra J. M, Brownstein M, Axelrod J. A specific and sensitive enzymatic-isotopic microassay for serotonin in tissues. Journal of Pharmacology and Experimental Therapeutics 1973; 186: 508
  • 7 Snyder S. H, Axelrod J, Zweig M. A sensitive and specific fluorescence assay for tissue serotonin. Biochemical Pharmacology 1965; 14: 831