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Thromb Haemost 1977; 37(02): 344-350
DOI: 10.1055/s-0038-1649235
Original Article
Schattauer GmbH

Ethanol-Induced Microaggregate Formation in Pig and Rabbit Blood

An in Vitro Study
Olle Elmér
1   Department of Surgery, University of Lund, S 221 85 Lund, Sweden.
,
Göran Göransson
1   Department of Surgery, University of Lund, S 221 85 Lund, Sweden.
,
Motonori Saku
1   Department of Surgery, University of Lund, S 221 85 Lund, Sweden.
,
Stig Bengmark
1   Department of Surgery, University of Lund, S 221 85 Lund, Sweden.
› Author Affiliations
Further Information

Publication History

Received 20 September 1976

Accepted 06 January 1977

Publication Date:
03 July 2018 (online)

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Summary

Increased microaggregate formation was found after mixing ethanol with blood from pig and rabbit in vitro, measured with Swank’s Screen Filtration pressure method. Final ethanol concentrations were in the range found in ethanol-intoxication in man. No rise in SFP was noticed when plasma with 10,000 platelets/μl was used. It is therefore doubtful that altered plasma proteins caused the rise in SFP. It is suggested that if a direct effect of ethanol upon platelet aggregation exists in vivo, it may be of importance in acute ethanol intoxication and in chronic alcoholism.

 

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