Factor VIII:C Levels during Oral Anticoagulation and after Its Withdrawal

Thromb Haemost 1995; 74(06): 1609-1610
DOI: 10.1055/s-0038-1649992

Letter to the Editor

Schattauer GmbH Stuttgart

Authors

Gualtiero Palareti

Dept. Angiology and Blood Coagulation, University Hospital S. Orsola, Bologna, Italy
Cristina Legnani

Dept. Angiology and Blood Coagulation, University Hospital S. Orsola, Bologna, Italy
Mirella Frascaro

Dept. Angiology and Blood Coagulation, University Hospital S. Orsola, Bologna, Italy
Giuliana Guazzaloca

Dept. Angiology and Blood Coagulation, University Hospital S. Orsola, Bologna, Italy
Sergio Coccheri

^*Chair, University Hospital S. Orsola, Bologna, Italy

References
1 Palareti G, Legnani C, Guazzaloca G, Frascaro M, Grauso F, De Rosa V, Fortunato G, Coccheri S. Activation of blood coagulation after abrupt or stepwise withdrawal of oral anticoagulants-a prospective study. Thromb Haemost 1994; 72: 222-226
2 van Wersch JW J. Non-vitamin K-dependent clotting factors during oral anticoagulant treatment. Blood Coagulat Fibrinol 1992; 3: 727-730
3 Koster T, Blann AD, Briët E, Vandembroucke JP, Rosendaal FR. Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis. Lancet 1995; 345: 152-155
4 Poller L, Thomson J. Evidence for rebound hypercoagulability after stopping anticoagulants. Lancet 1964; 2: 62-64
5 Poller L, Thomson J. Reduction of “rebound” hypercoagulability by gradual withdrawal (“tailing off”) of oral anticoagulants. Br Med J 1965; 1: 1476-1477