An Attempt at Predicting Postoperative Deep Vein Thrombosis by Preoperative Coagulation Studies in Patients Undergoing Total Hip Replacement

Dennis W T Nilsen; Miladin Jeremic; Odd K Weisert

doi:10.1055/s-0038-1650050

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 1980; 43(03): 194-197
DOI: 10.1055/s-0038-1650050

Original Article

Schattauer GmbH Stuttgart

An Attempt at Predicting Postoperative Deep Vein Thrombosis by Preoperative Coagulation Studies in Patients Undergoing Total Hip Replacement

Authors

Dennis W T Nilsen

The Oslo Emergency Medical Centre, University Hospital of Ullevål, Oslo and State Laboratory of Microbiology, Department of Immunohaematology and Blood Transfusion, Lillehammer, Norway
Miladin Jeremic

The Oslo Emergency Medical Centre, University Hospital of Ullevål, Oslo and State Laboratory of Microbiology, Department of Immunohaematology and Blood Transfusion, Lillehammer, Norway
Odd K Weisert

The Oslo Emergency Medical Centre, University Hospital of Ullevål, Oslo and State Laboratory of Microbiology, Department of Immunohaematology and Blood Transfusion, Lillehammer, Norway

Abstract

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Summary

Preoperative levels of fibrinogen, factors V, VII, VIII and antithrombin III were measured in 25 consecutive patients undergoing total hip replacement. Deep vein thrombosis (D.V.T.) was detected by fibrinogen-uptake test in 60% of the patients. The preoperative fibrinogen level was significantly higher (p < 0.05), and serum antithrombin III was markedly lower (p ≦ 0.1) in patients with postoperative D.V.T. The quotient of fibrinogen to serum antithrombin III was significantly higher (p < 0.01) in patients with D.V.T. This quotient may serve as an additional parameter to other clinical and laboratory tests in prediction of postoperative D.V.T. following hip surgery.

Keywords

Preoperative coagulation factors - Postoperative thrombosis in hip surgery

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Referenzen

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