Factor V Leiden and Sickle Cell Disease

Thromb Haemost 1996; 75(05): 859-860
DOI: 10.1055/s-0038-1650381

Letter to the Editor

Schattauer GmbH Stuttgart

Authors

M A Laffan

The Department of Haematology, Royal Postgraduate Medical School, London, UK
T Vulliamy

The Department of Haematology, Royal Postgraduate Medical School, London, UK
E Schmitz

The Department of Haematology, Royal Postgraduate Medical School, London, UK
D Swisky

The Department of Haematology, Royal Postgraduate Medical School, London, UK

References
1 Takamiya O, Ishida F, Kodaira H, Kitano K. APC-resistance and Mnl I genotype (Gin 506) of coagulation factor V are rare in Japanese population. Thromb Haemost 1995; 74: 996
2 Fujimara H, Kambayashi J, Monden M, Kato H, Miyata T. Coagulation Factor V Leiden mutation may have a racial background. Thromb Haemost 1995; 74: 1381-1382
3 Francis Jr RB. Platelets, coagulation, and fibrinolysis in sickle cell disease: their possible role in vascular occlusion. Blood Coagul Fibrinolysis 1991; 2: 341-353
4 Dahlbäck B. Factor V gene mutation causing inherited resistance to activated protein C as a basis for venous thromboembolism. J Intern Med 1995; 237: 221-227
5 Bertina RM, Koeleman BP, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-67
6 Rees C, Cox M, Clegg J. World distribution of factor V Leiden. Lancet 1995; 346: 1133-1134