Summary
Platelet adhesiveness to glass was determined in several groups of women. Increases
were found in women developing thrombovascular symptoms while taking combined oral
contraceptives, compared to both normal women and asymptomatic users of oral contraceptives.
Despite this increase, overlap of the groups did not permit discrimination between
symptomatic and asymptomatic women. However, it is possible, that in concert with
other coagulation changes, platelet adhesiveness to glass may prove adjunctive in
defining women at increased risk of developing thrombovascular symptoms while taking
oral contraceptives, and further define the mechanism of the increased risk.