Thrombosis and Haemostasis, Inhaltsverzeichnis Thromb Haemost 1961; 6(02): 381-385DOI: 10.1055/s-0038-1654569 Vorläufige Mitteilungen — Preliminary Reports — Communications Préliminaires Schattauer GmbH The Influence of Some Anticoagulants and Fibrinolytic Substances on Mice Fibroblasts (Strain L) in Tissue Culture K Peters 1 Department of Radiology (Head: Prof. Dr. R. Bauer) and the Department of Surgery (Head: Prof. Dr. W. Dick) of the University of Tübingen , P Matis 1 Department of Radiology (Head: Prof. Dr. R. Bauer) and the Department of Surgery (Head: Prof. Dr. W. Dick) of the University of Tübingen› InstitutsangabenArtikel empfehlen Abstract Artikel einzeln kaufen Summary The action of some anticoagulants and fibrinolytic substances on the culture of mice fibroblasts is described. Actase and streptokinase show a relatively high toxicity. Beta-heparins are more toxic than alpha-heparins. For pentosans the cytotoxic action is inversely proportional to the molecular weight. Marcoumar is more toxic than coumarin without anticoagulant activity. Variations of the concentration of factors VII, IX and X are of no importance for the cells. Cells 4 hours after explantation are not basically more sensitive than cells 24 hours after explantation. Volltext Referenzen References (1) Fischer A. Die Bindung yon Heparin an lebende Zellen. Scand. Arch. Physiol. 75: 121 1936; (2) Fischer A. Über die Wirkung des Heparins auf das Wachstum von Gewebezellen m vitro. Protoplasma 26: 344 1936; (3) Peters K. Fortschr. Röntgenstr. 88: 50 1958; (4) Schmidt J, Stockinger L. Zellwachstum und Dicumarine. Wien. Z. inn. Med. 32: 67 1952; (5) Zakrzewski Z. Untersuchungen über den Einfluß von Heparin auf das Wachstum von Sarkomzellen in vitro. Z. Krebsforsch. 36: 513 1932; (6) Zakrzewski Z. Die Rolle des Prothrombins und Heparins bei der Proliferation und Differenzierung von Geweben. Untersuchungen in vitro. Arch. exp. Zellforsch. 13: 152 1932;
