Thrombosis and Haemostasis, Table of Contents Thromb Haemost 1966; 16(01/02): 153-162DOI: 10.1055/s-0038-1655634 Originalarbeiten — Original Articles — Travaux Originaux Schattauer GmbH Microtubules and Microfibrils in Human Platelets J. J Sixma 1 Centre for Medical Electronmicroscopy (Head: I. Molenaar, M. D.), State University, Beetsstraat, Utrecht, The Netherlands , I Molenaar 1 Centre for Medical Electronmicroscopy (Head: I. Molenaar, M. D.), State University, Beetsstraat, Utrecht, The Netherlands › Author AffiliationsRecommend Article Abstract Buy Article Summary The microtubules and microfibrils of human platelets are described. They are studied under conditions that give as little alterations as possible. Conclusions on their localisation in vivo are drawn and their possible role in maintaining the platelet shape is discussed. Full Text References References 1 Bessis M, Burstein M. Etudes sur le throbocytes au microscope électronique. Rev. Hémat 3: 48 1948; 2 Fawcett D. W, Witebsky F. Observations on the ultrastructure of nucleated erythrocytes and thrombocytes. Z. Zellforsch 62: 785 1964; 3 Ledbetter M. C, Porter K. R. A microtubule in plant cell fine structure. J. Cell. Biol 19: 239 1963; 4 Sandborn E, Koen P. F, McNabb J. D, Moore G. Cytoplasmic microtubules in mammalian cells. J. Ultrastruct. Res 11: 123 1964; 5 Behnke O. A preliminary report on “microtubules” in undifferentiated and differentiated vertebrate cells. J. Ultrastruct. Res 11: 139 1964; Further studies on microtubules. A marginal bundle in human and rat thrombocytes. J. Ultrastruct. Res. 13:469-477 (1965) 6 Bessis M, Breton-Gorius J. Les microtubules et les fibrilles dans les plaquettes étalées. Nouv. Rev. franc. Hémat 5: 657 1965; 7 Sabatini D. D, Bensch K, Barrnet R. J. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation. J. Cell. Biol 17: 19 1963; 8 Watson M. L. Staining of tissue sections for electron microscopy with heavy metals. J. biophys. biochem. Cytol 4: 475 1958; 9 Reynolds E. S. The use of leadcitrate at high pH as an electronopaque stain in electron microscopy. J. Cell. Biol 17: 208 1963; 10 Feissly R, Gautier A, Marcovici I. Nouveau procédé d’examen des thrombocytes au microscope électronique. Note préliminaire. Rev. Hémat 12: 397 1957; 11 Zucker M. B, Borelli J. Reversible alterations in platelet morphology produced by anticoagulants and by cold. Blood 9: 602 1954; 12 Slautterback D. B. Cytoplasmic microtubules. I. Hydra. J. Cell. Biol 18: 367 1963; 13 Wolfe S. L. Isolated microtubules. J. Cell. Biol 25: 468 1965; 14 Fawcett D. W. Cited by D. B. Slautterback (12) 15 Lüscher E. F. Personal communication. 16 Falçao L. Personal communication. 17 Haydon G. B, Taylor D. A. Microtubules in hamster platelets. J. Cell. Biol 26: 673 1965; 18 Silver M. D. Cytoplasmic microtubules in rabbit platelets. Z. Zellforsch 68: 474-480 1965;
