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               Background Echocardiography is an important technique in neonatal care. The heart of a premature
               baby is known to be different from that of a term baby, and there is a paucity of
               literature regarding reference cardiac measurements for this population, especially
               for the very low birth weight (VLBW) infants.
            
            
               Objective We aimed to present reference values for echocardiography in VLBW preterm infants.
            
            
               Study Design This was a retrospective observational study taking place over an 11-year period.
               We collected data from the reports of echocardiographic examinations performed in
               a population of preterm infants born with gestational age ≤ 32 weeks and birth weight
               (BW) ≤ 1,500 g in the first week of life.
            
            
               Results Our study population included 1,244 preterm infants. We found BW to be an adequate
               and practical variable to use in relation to the cardiac measurements. We propose
               reference values for seven cardiac measurements presented in tables for each 100 g
               weight subgroup.
            
            
               Conclusion Our study, to the best of our knowledge, has the largest sample of VLBW preterm infants
               and provides easy-to-use information on cardiac measurements by echocardiography for
               both pediatric cardiologists and neonatologists.
            
         
         Keywords
echocardiography - premature infant - very low birth weight infant