Geburtshilfe Frauenheilkd 2018; 78(10): 90
DOI: 10.1055/s-0038-1671017
Poster
Donnerstag, 01.11.2018
Gynäkologische Onkologie III
Georg Thieme Verlag KG Stuttgart · New York

Change of patient perceptions of chemotherapy side effects in breast and ovarian cancer patients

J Frindte
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
B Ataseven
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
P Harter
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
G Göke
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
J Podkowinkski
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
C Vogt
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
V Bluni
2  Kliniken Essen Mitte, Senologie/Interdisziplinäres Brustzentrum, Essen, Deutschland
,
M Vincent
2  Kliniken Essen Mitte, Senologie/Interdisziplinäres Brustzentrum, Essen, Deutschland
,
A Traut
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
F Heitz
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
S Kümmel
2  Kliniken Essen Mitte, Senologie/Interdisziplinäres Brustzentrum, Essen, Deutschland
,
S Prader
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
M Bommert
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
S Schneider
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
,
A du Bois
1  Kliniken Essen Mitte, Gynäkologie und gynäkologische Onkologie, Essen, Deutschland
› Author Affiliations
Further Information

Publication History

Publication Date:
20 September 2018 (online)

 

Objective:

Studies in 1983, 1993, and 2002 identified patient perceptions (PP) and individual ranking of chemotherapy side effects (CSE). We aimed to update this survey and evaluate changes in patient perceptions a further decade later.

Methods:

Patients with breast (BC) and ovarian cancer (OC) were recruited in this prospective study before start of chemotherapy. At week 12 +/- 3 weeks after chemotherapy initiation patients were asked to identify out from 72 cards displaying potential physical and non-physical CSE the ten most burdensome and rank them finally to top five by severity. Results are reported for the entire group and in comparison to published data.

Results:

The most severe CSE among 126 patients (85 BC and 41 OC) was “difficulty sleeping” compared to “vomiting” in 1983, “nausea” in 1993, and “affects my family/partner” in 2002 (table 1). “Loss of hair” remained a top concern over all studies. The most severe CSE in BC patients was “loss of hair” in contrast to “difficulty sleeping“ in OC patients.

Tab. 1:

Comparison of the ranking of side effects from 1983 – 2017

Ranking of side effects

1983
(Coates et al.)

1993
(Griffin et al.)

2002
(Carelle et al.)

2017
Current study

1

Vomiting

Nausea

Affects my family or partner

Difficulty sleeping

2

Nausea

Constantly tired

Loss of hair

Affects my family or partner

3

Loss of hair

Loss of hair

Constantly tired

Loss of hair

4

Thought of coming treatment

Thought of coming treatment

Affects my work, home duties

Numbness in limbs

Conclusions:

PP of CSE have changed markedly over decades. Especially taxane related CSE are reported more frequently. However, “loss of hair” has remained an unsolved problem over decades.