Abstract
Objectives Determining surgical trends and outcomes for sinonasal tumors is challenging given
their low incidence and heterogeneous pathology. This study utilized the National
Cancer Database (NCDB) to identify trends and outcomes associated with surgical management
of sinonasal tumors.
Design Retrospective database analysis.
Setting National Cancer Database.
Participants Patients with sinonasal malignancies identified from the NCDB between 2010 and 2015.
Main Outcome Measures The primary outcome was the choice of surgical therapy used for sinonasal tumor resection:
endoscopic versus open approach. Each was cohort analyzed with respect to various
demographic and clinicopathologic factors. A treatment effect model was used to identify
potential differences between surgical approaches. Survival was evaluated using Kaplan–Meier
analysis.
Results A total of 10,193 patients with sinonasal malignancies were identified in the NCDB
database; of these, 2,292 had a documented subsite, histology, and definitive surgical
treatment with documented surgical approach and were included in the analysis. About
71.9% of patients had an open approach and 28.1% a purely endoscopic procedures. Tumor
histology, treatment facility type, margin status, and length of stay were all variables
that were associated with significant differences between the open and endoscopic
cohort. Five-year survival rates for the open and endoscopic cohorts were not significantly
different (59.6 and 60.8%, respectively).
Conclusions Assessment of the NCDB revealed that 28% patients with sinonasal malignancy were
selected for endoscopic surgery. These patients had comparable oncologic outcomes
to open resection.
Keywords
sinonasal tumor - sinonasal malignancies - population-based - NCDB
