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CC BY-NC-ND 4.0 · AJP Rep 2018; 08(04): e261-e263
DOI: 10.1055/s-0038-1675376
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Recurrent Cholangiocarcinoma in Pregnancy: A Case Report

Antonia P. Francis
1   Department of Obstetrics and Gynecology, New York University Langone Health, New York, New York
,
Michelle Chang
2   Department of Medicine, Columbia University Irving Medical Center, New York, New York
,
Cara D. Dolin
4   Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia
,
Judith Chervenak
1   Department of Obstetrics and Gynecology, New York University Langone Health, New York, New York
,
Elyce Cardonick
3   Department of Obstetrics and Gynecology, Cooper University Health Care, Camden, New Jersey
› Author Affiliations
Further Information

Publication History

22 February 2018

05 September 2018

Publication Date:
12 November 2018 (online)

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Abstract

Hepatobiliary malignancies during pregnancy are extremely rare and portend a poor prognosis. There are only seven published cases of cholangiocarcinoma in an obstetrical patient, all are cases of primary cholangiocarcinoma (1–7). Herein, we describe the first case of recurrent cholangiocarcinoma during pregnancy. The patient did not receive chemotherapy during pregnancy and required prolonged hospitalizations for nutritional and intensive medical support. She delivered preterm, at 30 2/7 weeks gestation, after developing pre-eclampsia with severe features. The infant was healthy, with no malformations, and currently exhibits no neurological or behavioral sequelae at 8months of age. We discuss themanagement considerations inherent to this complex clinical scenario including metastatic disease severity, ethical considerations, and palliative care treatment options.

Keywords

cancer - pregnancy - cholangiocarcinoma - hepatobiliary
 

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