Endoscopy 2019; 51(04): S116-S117
DOI: 10.1055/s-0039-1681512
ESGE Days 2019 oral presentations
Saturday, April 6, 2019 14:30 – 16:00: CRC screening South Hall 1B
Georg Thieme Verlag KG Stuttgart · New York

EFFECT OF THE NATIONAL SCREENING PROGRAM ON THE COLORECTAL CANCER INCIDENCE AND MORTALITY REDUCTION IN THE CZECH REPUBLIC

S Suchanek
1   1st Faculty of Medicine, Charles University, Military University Hospital, Department of Internal Medicine, Prague, Czech Republic
,
O Ngo
2   Faculty of Medicine, Masaryk University, Institute of Biostatistics and Analyses, Brno, Czech Republic
,
T Grega
1   1st Faculty of Medicine, Charles University, Military University Hospital, Department of Internal Medicine, Prague, Czech Republic
,
O Majek
2   Faculty of Medicine, Masaryk University, Institute of Biostatistics and Analyses, Brno, Czech Republic
,
M Zavoral
1   1st Faculty of Medicine, Charles University, Military University Hospital, Department of Internal Medicine, Prague, Czech Republic
› Author Affiliations
Further Information

Publication History

Publication Date:
18 March 2019 (online)

Also available ateRef
 

Aims:

The organized non-population based National Colorectal Cancer (CRC) Screening Program in the Czech Republic has been running since year 2000. In January 2014, the transition to population-based setting has been implemented. The main target lesions of the CRC screening program are the adenomas and early cancers. Therefore, the relation between number of colonoscopies/endoscopic polypectomies and CRC incidence and mortality decrease was evaluated.

Methods:

The analysis was based on the aggregate data from the Health Insurance Companies Databases, Preventive Colonoscopies Database and National Oncology Registry.

Results:

Between years 2000 and 2015, there was significant reduction of the CRC incidence (18.4%) and mortality (32.4%) observed. The number of colonoscopies and endoscopic polypectomies has been raising continuously every year. In 2015, there were 264,399 colonoscopies performed from the following indications: 227,905 (86.2%) symptoms, follow-up and therapy; 23,463 (8.9%) FIT positivity and 13,031 (4.9%) screening at age ≥55. In the same year, overall 60,120 endoscopic polypectomies were done (22,7% of all colonoscopies) in following age groups: 5,272 in age < 50; 5,627 in age 50 – 54 and 49,221 in age ≥55. In 36,494 colonoscopies performed within the organized CRC screening program in year 2015, there were 14,085 (38.6%) adenomas and 969 (2.7%) cancers diagnosed. 40.0% of the adenomas were advanced (≥10 mm, villous component, high-grade dysplasia). Majority of the cancers found were in stage I (45%) and II (18%).

Conclusions:

There is a very likely connection between the high number of diagnostic/therapeutic colonoscopies and CRC incidence and mortality reduction. To assess the benefit of the screening program to this effect, the comprehensive individual data from the new National Registry of Reimbursed Health Services needs to be evaluated.

Supported by the Czech Ministry of Health grant No. 17 – 31909A and projects MO1012 and Progres Q28/LF1.