Endoscopy 2019; 51(04): S212
DOI: 10.1055/s-0039-1681801
ESGE Days 2019 ePosters
Friday, April 5, 2019 09:00 – 17:00: Colon and rectum ePosters
Georg Thieme Verlag KG Stuttgart · New York

COLORECTAL CANCER INCIDENCE AND THE PREVALENCE OF PRECURSOR LESIONS IN YOUNGER ADULTS

D Penz
1   Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
2   Austrian Society of Gastroenterology and Hepatology (OEGGH), Vienna, Austria
,
A Ferlitsch
3   Barmherzige Brüder, Vienna, Austria
,
E Waldmann
1   Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
2   Austrian Society of Gastroenterology and Hepatology (OEGGH), Vienna, Austria
,
D Pammer
1   Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
2   Austrian Society of Gastroenterology and Hepatology (OEGGH), Vienna, Austria
,
B Majcher
1   Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
2   Austrian Society of Gastroenterology and Hepatology (OEGGH), Vienna, Austria
,
I Gessl
2   Austrian Society of Gastroenterology and Hepatology (OEGGH), Vienna, Austria
,
A Hinterberger
1   Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
2   Austrian Society of Gastroenterology and Hepatology (OEGGH), Vienna, Austria
,
A Szymanska
1   Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
2   Austrian Society of Gastroenterology and Hepatology (OEGGH), Vienna, Austria
,
A Asaturi
1   Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
2   Austrian Society of Gastroenterology and Hepatology (OEGGH), Vienna, Austria
,
M Trauner
1   Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
,
M Ferlitsch
1   Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
2   Austrian Society of Gastroenterology and Hepatology (OEGGH), Vienna, Austria
› Author Affiliations
Further Information

Publication History

Publication Date:
18 March 2019 (online)

 

Aims:

In the USA, Colorectal cancer (CRC) incidence and mortality decreases among the screening population. However more often younger (< 50y) get diagnosed with CRC. Therefore, the American-Cancer-Society recommend to start screening colonoscopy (SC) at the age of 45. Aim of our study is to assess the CRC incidence in Austria within different age groups and compare it with the occurrence of precursor lesions.

Methods:

266.592 screening colonoscopies were analyzed from 2008 – 2018 within the "Austrian-screening-program". The incidence (per 100.000) of colorectal cancer with the data from Statistic Austria and the prevalence of precursors within the Austria screening program were assessed within different age groups and compared among adults over and under 50years.

Results:

9341 (3,5%) patients were below the age of 50 and 257.251 (96,5%) were over 50 years old. CRC-incidence under the age of 50 was 7,6 (♂) & 6,6 (♀) in 1985; 7,5 (♂) & 6,5 (♀) in 1995; 8,7 (♂) & 7,7 (♀) in 2005 and 9,8 (♂) & 8,8 (♀) in 2015. Incidences for patients over 50 was 192,7 (♂) & 156,8 (♀) in 1985; 215,3 (♂) & 160,7 (♀) in 1995; 212,3 (♂) & 144,0 (♀) in 2005 and 148,6 (♂) & 95,3 (♀) in 2015. The prevalence of advanced adenomas changed from 5,5% (♂) & 2,1% (♀) in 2008 to 7,4% (♂) & 8,7% (♀) in 2018 within patients under 50 and from 9,5% (♂) & 5,2% (♀) to 6,9% (♂) & 4,9% (♀) within those over 50 years.

The number needed to Screen (NNS) for an Adenoma was 5 within men aged 45 – 49, as well as among 50 – 54-years old. Within women NNS of 8 was also identically for both age groups.

Conclusions:

CRC incidence, as well as the occurrence of precursor advanced adenomas decreased within patients over 50 in the last years, while it is increasing among individuals under 50. The NNS for an adenoma is identically among patients aged 45 – 49 and 50 – 54. Therefore, the age for starting SC should be diminished to 45.