Semin Neurol 2019; 39(02): 151-152
DOI: 10.1055/s-0039-1685173
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.


Arash Salardini
1  Behavioral Neurology, Yale School of Medicine, New Haven, Connecticut
2  Yale Memory Clinic, Yale School of Medicine, New Haven, Connecticut
3  Yale ADRC, Yale School of Medicine, New Haven, Connecticut
› Author Affiliations
Further Information

Publication History

Publication Date:
29 March 2019 (online)

It is with pleasure that I present this issue of Seminars in Neurology on “dementias.” With rapid advances in this field, the clinical care of dementia is no longer viewed in the fatalistic terms it once was. Although most pathologies causing dementia are not currently treatable, the disease has become more manageable and its diagnosis more accurate. Strategies that maximize daily functions and modify lifestyles now succeed in delaying the onset of dementia and improving the quality of life. Neurologists with their background in neurosciences are particularly well placed to take advantage of these recent advances in diagnosis and management of prodromal disease. In spite of this, cognitive disorders occupy a surprisingly small portion of most residency curricula and neurology textbooks.

With this in mind, we set out to make this volume a stand-alone dementia primer for the practicing neurologist. We have included separate introductory chapters on the following:

  • An overview of primary dementias (Salardini).

  • Interpretation of biomarker data in diagnosis of dementia (Salardini).

  • Mild cognitive impairment (Qarni and Salardini).

  • Behavioral and cognitive symptom management in dementias (Tisher and Salardini).

In line with the feedback from our general neurology colleagues, we included updates on the following:

Zoom Image
Arash Salardini, MD
  • Neuroimaging of dementias (Mahalingam and Chen of Yale University).

  • Autoimmune encephalitides (Ferguson and Wesley of Yale University and Trinity College Dublin).

In depth, treatments of primary dementias were delegated to acknowledged world leaders of their given topics. These papers are resources for readers interested in more advanced treatment of primary dementias:

  • Alzheimer's disease including its focal presentations (Villain and Dubois of Pitié Salpêtrière).

  • Current and future treatments in Alzheimer's disease (Atri of BSHR).

  • Frontotemporal lobar degeneration (Siavasathiaseelan and Warren of University College London).

  • Rare tauopathies (Ali and Josephs of the Mayo Clinic).

  • Parkinson's disease dementia and Lewy body disease (Tinaz, Bilgic, Sezgin and Emre of Istanbul University).

  • Vascular dementia (Paradise and Sachdev of University of New South Wales).

In preparing this issue, our aim has been to produce a comprehensive, in depth, yet accessible volume for practicing neurologists. Cognitive neurology is a fascinating and rewarding area of neurology. I hope we have conveyed some of this interest to our appreciated readers, and in the process succeeded in providing useful information in an easy-to-read format.