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Semin Neurol 2019; 39(03): 369-382
DOI: 10.1055/s-0039-1687837
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Herpesvirus Infections of the Central Nervous System

Tehmina Bharucha   *
1   Department of Biochemistry, University of Oxford, London, United Kingdom
,
Catherine F. Houlihan   *
2   London School of Hygiene and Tropical Medicine, London, United Kingdom
3   Division of Infection and Immunity, University College London, London, United Kingdom
,
Judith Breuer 
3   Division of Infection and Immunity, University College London, London, United Kingdom
› Author Affiliations
Further Information

Publication History

Publication Date:
02 August 2019 (online)

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Abstract

There are over 200 herpesvirus species, of which 10 affect humans. Each of these 10 herpesviruses has a unique clinical syndrome, but common to all is their ability to cause infection and pathology in the central nervous system. In this article, we discuss the epidemiology, clinical presentation, diagnostic modalities, treatment, sequelae, and availability of vaccination of each of the following herpesviruses: herpes simplex virus 1 and 2, varicella zoster virus, human cytomegalovirus, human herpesvirus 6A, 6B, and 7, Epstein–Barr virus, human herpesvirus 8, and simian herpesvirus B.

Keywords

neurological infections - herpesviruses - diagnosis

* Joint first authors.


 

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