Is Delaying Cord Clamping until Placenta Delivery Beneficial? Oxygen Saturation and Heart Rate Transition during the Initial 5 Minutes after Delivery in Indian Healthy Newborns

Suchandra Mukherjee; Jignesh S. Bulsara; Manoja Kumar Das; Yogendra Waratakar; Anindya Kumar Saha; Sunil Dubey; Pratima Mehta; Bini Gupta; Arun K. Singh; for Indian Delayed Cord Clamp Study Group

doi:10.1055/s-0039-1688982

American Journal of Perinatology, Inhaltsverzeichnis

Am J Perinatol 2020; 37(07): 738-744
DOI: 10.1055/s-0039-1688982

Original Article

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Is Delaying Cord Clamping until Placenta Delivery Beneficial? Oxygen Saturation and Heart Rate Transition during the Initial 5 Minutes after Delivery in Indian Healthy Newborns

Suchandra Mukherjee

¹Department of Neonatology, Institute of Post Graduate Medical Education & Research, Kolkata, West Bengal, India

,

Jignesh S. Bulsara

²Department of Obstetrics and Gynaecology, Shreemad Rajchandra Hospital, Dharampur, Valsad, Gujarat, India

,

Manoja Kumar Das

³The INCLEN Trust International, New Delhi, India

,

Yogendra Waratakar

⁴Department of Pediatrics, Shreemad Rajchandra Hospital, Dharampur, Valsad, Gujarat, India

,

Anindya Kumar Saha

¹Department of Neonatology, Institute of Post Graduate Medical Education & Research, Kolkata, West Bengal, India

,

Sunil Dubey

⁵Medical Administration, Shreemad Rajchandra Hospital, Dharampur, Valsad, Gujarat, India

,

Pratima Mehta

⁵Medical Administration, Shreemad Rajchandra Hospital, Dharampur, Valsad, Gujarat, India

,

Bini Gupta

³The INCLEN Trust International, New Delhi, India

,

Arun K. Singh

⁶Rashtriya Bal Swasthya Karyakram, Ministry of Health & Family Welfare, Government of India, New Delhi, India

,

for Indian Delayed Cord Clamp Study Group

› Institutsangaben

Abstract

Objective This study aimed to compare the preductal oxygen saturation (SpO₂) and heart rate (HR) in newborns during the initial 5 minutes after birth with delayed cord clamping (DCC) and early cord clamping (ECC) practices at sea level.

Study Design This prospective observational study included newborns born at >34 weeks vaginally (Dharampur, Gujarat) or through caesarean section (CS) (Kolkata, West Bengal). In Dharampur, the newborns received ECC practice (8 weeks) followed by DCC practice (10 weeks). In Kolkata, the newborns received ECC practice only (8 weeks).

Results The newborns with DCC (n = 170) had significantly higher SpO₂ (3–8%) throughout than those with ECC born either vaginally (n = 178) or through CS (n = 101). The newborns with DCC had slower rise in HR during the first 2 minutes than those with ECC. The 5th and 10th percentile values of SpO₂ for newborns with DCC practice were higher than those with ECC practice.

Conclusion The trends of SpO₂ and HR during the first 5 minutes after birth indicate a relatively smoother cardiopulmonary transition by delaying cord clamping till placental delivery compared with early clamping. The reference ranges can be used for Indian newborns born by uncomplicated vaginal delivery with DCC during the first 5 minutes.

Keywords

cord clamping - early - delay - oxygen saturation - hear rate - percentile - sea level

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