CC BY-NC-ND 4.0 · International Journal of Epilepsy 2018; 05(02): S15
DOI: 10.1055/s-0039-1694895
Abstracts of 20th Joint Annual Conference of Indian Epilepsy Society and Indian Epilepsy Association (ECON 2019)
Indian Epilepsy Society

Use of Early Childhood Epilepsy Severity Scale (E-Chess) in Classification and Prognostication of Children with West Syndrome: A Study from Tertiary Care Pediatric Neurology Centre

Mishra S.
1  Department of Neurology, S.C.B Medical College, Cuttack, Odisha, India
,
Mallick A. K.
1  Department of Neurology, S.C.B Medical College, Cuttack, Odisha, India
,
Mohanty G.
1  Department of Neurology, S.C.B Medical College, Cuttack, Odisha, India
,
Biswal N.
1  Department of Neurology, S.C.B Medical College, Cuttack, Odisha, India
› Author Affiliations

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Further Information

Publication History

Publication Date:
31 July 2019 (online)

  

Background: West syndrome is a type of pediatric epilepsy syndrome often associated with a grave prognosis. The aim of this study was to evaluate clinicoradiologically cases of West syndrome, to use E-chess scoring, and classify and use it for prognostication.

Materials and Methods: Prospective observational clinical study for 1 year in the pediatric neurology out patients department of S.C.B. Medical College, Cuttack, Odisha. Patients were included as a case of West syndrome when they met all three criteria: (1) developmental plateau or regression, (2) epileptic spasm, (3) hypsarrhythmia on electroencephalography (EEG) who came to our center for first time (with/without previous treatments) after informed consent. They were classified into three groups by E-chess scoring according to severity of disease ([Table 1]).

Table 1

Classification of patients by E-chess scoring according to severity of disease

Types

E-chess score

I

6–9

II

10–12

III

13–15

Results: The total number of children included in the study was 13. Mean age of presentation was 9.4 months. Maximum patients were males. Mean duration of the disease was 3 months. Most of the patients were having hypoxic ischemic sequel in MRI. Twenty-three percent patients were categorized into type-III, 31% into type-II, 46% into type-I. Types II and III were drug-resistant epilepsy with poor response.

Conclusion: West syndrome is one of the infantile epilepsy syndromes with grave prognosis. E-chess scoring is a good and useful scoring system for classification and prognostication. This can be used in OPD basis for categorization of West syndrome. The types II and III are drug-resistant varieties with poor response to drugs. They should be planned for surgical therapy.