Abstract
Patients with multiple myeloma often show skull bone involvement, although in most
cases this is manifested as skull erosion and large masses develop only rarely. Here
we report a patient who presented with a large cranial mass mimicking a subdural hematoma
with calcification. The tumor shrunk with 37.5 Gy of focal irradiation in 15 fractions
after biopsy. After irradiation the patient was treated with Bortezomib but died because
of adverse events. The differential diagnosis of lenticular lesion of the skull and
treatment strategy for large skull mass with myeloma cells are discussed.
Keywords
myeloma - skull mass - calcified hematoma
