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CC BY-NC-ND 4.0 · Eur J Dent 2012; 06(03): 340-345
DOI: 10.1055/s-0039-1698971
Original Article
Dental Investigation Society

The genetic basis of facial skeletal characteristics and its relation with orthodontics

Derya Germec Cakan
1   Department of Orthodontics, Faculty of Dentistry, Yeditepe University, Istanbul, TURKIYE
,
Feyza Ulkur
1   Department of Orthodontics, Faculty of Dentistry, Yeditepe University, Istanbul, TURKIYE
,
Tulin Uğur Taner
2   Department of Orthodontics, Faculty of Dentistry, Hacettepe University, Ankara, TURKIYE
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Publikationsdatum:
09. März 2020 (online)

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ABSTRACT

Successful treatment of any orthodontic problem depends on an appropriate diagnosis of its etiology. It is well known that the genetics, as well as environmental factors, play an important role on the etiology of skeletal anomalies. Recent studies and advances in genetic sciences allowed the orthodontists to better understand the effects of genetics on the etiology of dentofacial characteristics and pathologies which in turn supported the effects of the genes in the development of dentofacial complex. In orthodontic practice, the genetic basis of a skeletal anomaly should also be considered during the diagnosis. Therefore orthodontic treatment plan should be chosen accordingly. However, further genetic studies are required to clearly determine all the specific genes leading to a particular skeletal variability caused by the polygenic nature of craniofacial traits. This article includes the current information on the association between orthodontics and genetics, an outline of the evidence based impact of heredity on dentofacial development as a review of the etiological factors of skeletal anomalies from the genetic point of view. (Eur J Dent 2012;6:340-345)

Key words

Genetics - orthodontics - facial skeletal anomalies
 

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