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CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2019; 09(03): 085-090
DOI: 10.1055/s-0039-3400169
Original Article

A Preliminary Investigation for Standardization of Hydroalcoholic Extract of Mucuna pruriens (Kapikaccu): An Important Drug Used to Treat Parkinson’s Disease in Ayurveda

Gangadhara Swamy
1   Department of Anatomy, Subbaiah Institute of Medical Sciences and Research Centre, Shivamogga, Karnataka, India
,
Rajendra Holla
2   Department of Pharmacology, K. S. Hegde Medical Academy, Mangalore, Karnataka, India
,
Suresh R. Rao
1   Department of Anatomy, Subbaiah Institute of Medical Sciences and Research Centre, Shivamogga, Karnataka, India
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Abstract

Establishment of standardization for the Ayurvedic formulations is most important for its chemical compounds, biological action, and its quality reassurance in production and manufacturing of traditional herbal medicines. As most of the drugs are standardized, drug companies are using substitute drugs instead of true drugs. So, to make finest superiority drugs it is necessary to validate raw drugs. Observing the existing trend in mind, hydroalcoholic extract of Mucuna pruriens seeds (HAMP) was subjected to standardize the procedures for phytochemical tests. The separation of bioactive substances from HAMP was performed using both manual methods and high-profile thin layer chromatography. From the current study, it is revealed that the seed contains alkaloids, steroids, carbohydrates, tannins, flavonoids, and coumarins, which gave the medicine numerous therapeutic properties.

Keywords

hydroalcoholic extract of Mucuna pruriens - phytochemical analysis - HPTLC


Publication History

Received: 29 August 2019

Accepted: 10 September 2019

Article published online:
05 February 2020

© .

Thieme Medical and Scientific Publishers Private Ltd.
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