A Case of Giant Cell Tumour of Bone in a Dog

Margaux Blondel; Lucile Gros; Marie-Odile Semin; Maxence Delverdier; Sophie Palierne; André Autefage

doi:10.1055/s-0039-3400513

VCOT Open, Inhaltsverzeichnis

CC BY 4.0 · VCOT Open 2019; 02(02): e64-e69
DOI: 10.1055/s-0039-3400513

Case Report

Georg Thieme Verlag KG Stuttgart · New York

A Case of Giant Cell Tumour of Bone in a Dog

Authors

Margaux Blondel

¹Division of Small Animal Surgery, Department of Clinical Sciences, Ecole Nationale Vétérinaire de Toulouse, University of Toulouse, Toulouse, France
Lucile Gros

²Division of Diagnostic Imaging, Department of Clinical Sciences, Ecole Nationale Vétérinaire de Toulouse, University of Toulouse, Toulouse, France
Marie-Odile Semin

³Division of Pathology, Department of Biological and Fundamental Sciences, University of Toulouse, Ecole Nationale Vétérinaire de Toulouse, Toulouse, France
Maxence Delverdier

³Division of Pathology, Department of Biological and Fundamental Sciences, University of Toulouse, Ecole Nationale Vétérinaire de Toulouse, Toulouse, France
Sophie Palierne

¹Division of Small Animal Surgery, Department of Clinical Sciences, Ecole Nationale Vétérinaire de Toulouse, University of Toulouse, Toulouse, France
André Autefage

¹Division of Small Animal Surgery, Department of Clinical Sciences, Ecole Nationale Vétérinaire de Toulouse, University of Toulouse, Toulouse, France

Abstract

Case Description A 9-year-old neutered female mixed-breed dog was presented for the assessment of right pelvic limb lameness of 1-week duration. The lameness had progressed to non-weight bearing the day before presentation.

Diagnostic Findings Radiographic examination of the right stifle joint revealed a large purely lytic lesion affecting the proximal metaphysis and epiphysis of the right tibia associated with a pathological fracture of the tibial plateau. These findings, combined with histological evaluation of a bone biopsy performed under ultrasound-guidance, were suggestive of a giant cell tumour of bone.

Treatment and Outcome A limb-sparing procedure was attempted as first-line treatment. Curettage of the tumour was followed by coblation, and the defect was filled with polymethyl methacrylate bone cement. Physical and radiographic follow-up examinations 1, 2 and 3 months after surgery revealed improved functional outcome and minor progression of osteolysis. However, local recurrence was apparent 5 months after initial surgery and the limb was therefore amputated.

Clinical Relevance Giant cell tumour of bone is rare in dogs. In humans, the traditional surgical management is curettage. This treatment was attempted here for the first time in a dog and the short-term outcome was satisfactory. However, in this particular case, local control of the tumour was unsuccessful.

Keywords

giant cell - bone tumours - dogs - curettage - PMMA bone cement filling

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Referenzen

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