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CC BY-NC-ND 4.0 · Indian Journal of Neurosurgery 2020; 9(03): 204-207
DOI: 10.1055/s-0039-3402591
Case Report

Cerebellar Cryptococcoma in an Immunocompetent Adult: A Rare Occurrence Report of a Case and Review of Literature

Manish Kumar
1   Department of Neurosurgery, Postgraduate Institute of Medical Education & Research, Chandigarh, India
,
Ankur Bajaj
1   Department of Neurosurgery, Postgraduate Institute of Medical Education & Research, Chandigarh, India
,
Manoj Kumar Tewari
1   Department of Neurosurgery, Postgraduate Institute of Medical Education & Research, Chandigarh, India
,
Paramjit Singh
2   Department of Radio-diagnosis and Imaging, Postgraduate Institute of Medical Education & Research, Chandigarh, India
,
Bishan Das Radotra
3   Department of Histopathology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
› Author Affiliations Funding None.
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Abstract

This study reports a rare case of cryptococcoma of the brain and review the related literature. An intracranial lesion, in a healthy, middle-aged adult who underwent surgery with a preoperative diagnosis of neoplastic/metastatic lesion, which turned out to be cryptococcoma, is being reported. Histopathological examination revealed that this immunocompetent patient had cryptococcoma of the cerebellum. He responded to antifungal chemotherapy (amphotericin B initially for 2 weeks and later oral fluconazole for 10 weeks) very well. Occurrence of cryptococcomas in immunocompetent patients is rare and responds to antifungal chemotherapy very well. Only six cases (including this) have been reported in literature till now.

Keywords

cryptoccocal infection - cerebellar cryptococcoma - neurotropic - immunocompetent


Publication History

Article published online:
11 February 2020

© 2020. Neurological Surgeons’ Society of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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