Platelet-Rich Fibrin in Coverage of Gingival Recession: A Systematic Review and Meta-Analysis

Miguel Augusto Riquelme Rodas; Bruna Luísa de Paula; Victor Fabrizio Cabrera Pazmiño; Flávia Ferraz dos Santos Lot Vieira; Joel Ferreira Santiago Junior; Elcia Maria Varize Silveira

doi:10.1055/s-0040-1701907

European Journal of Dentistry, Table of Contents

CC BY-NC-ND 4.0 · Eur J Dent 2020; 14(02): 315-326
DOI: 10.1055/s-0040-1701907

Review Article

Platelet-Rich Fibrin in Coverage of Gingival Recession: A Systematic Review and Meta-Analysis

Authors

Miguel Augusto Riquelme Rodas

¹Universidade do Sagrado Coração (USC), Bauru, São Paulo, Brazil
Bruna Luísa de Paula

¹Universidade do Sagrado Coração (USC), Bauru, São Paulo, Brazil
Victor Fabrizio Cabrera Pazmiño

²Department of prosthesis, Hospital for Rehabilitation of Craniofacial Anomalies (HRAC), University of São Paulo (USP), Bauru, São Paulo, Brazil
Flávia Ferraz dos Santos Lot Vieira

¹Universidade do Sagrado Coração (USC), Bauru, São Paulo, Brazil
Joel Ferreira Santiago Junior

¹Universidade do Sagrado Coração (USC), Bauru, São Paulo, Brazil
Elcia Maria Varize Silveira

¹Universidade do Sagrado Coração (USC), Bauru, São Paulo, Brazil

Abstract

This systematic review and meta-analysis sought to evaluate the efficacy of platelet-rich fibrin (PRF) membranes versus subepithelial connective tissue grafts (SCTGs) in the coverage of Miller class I and II gingival recessions. After the inclusion and exclusion criteria were applied, the quality of seven articles (Cohen’s Kappa = 0.9) was evaluated using the Jadad scale. The MEDLINE/PubMed, Cochrane, and Web of Science databases were consulted, and manual searches were performed in the most popular periodontics journals. The studies included considered a total of 122 patients, 203 surgical fields on which SCTGs were used, and 205 surgical fields on which PRF was used. The parameters analyzed were probing depth, clinical attachment level, gingival recession, and keratinized mucosa. The minimum follow-up period accepted was 6 months. A statistically significant difference between the SCTG and PRF groups was found only in the case of keratinized mucosa. However, gingival recession, clinical attachment level, and probing depth parameters in the PRF group were found to be statistically equal to those of the SCTG group (the gold standard) (p ≥0.05). PRF membranes were determined to be a promising alternative to autogenous gingival grafts in the treatment of Miller class I and II gingival recessions.

Keywords

connective tissue - platelet-rich fibrin - gingival recession - systematic review

Full Text

References

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