Endoscopy 2020; 52(S 01): S74
DOI: 10.1055/s-0040-1704224
ESGE Days 2020 oral presentations
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EDUCATIONAL TELEPHONE INTERVENTION NEAR THE COLONOSCOPY AS A SALVAGE STRATEGY AFTER A BOWEL PREPARATION FAILURE. A MULTICENTRE RANDOMIZED TRIAL

MA Alvarez-Gonzalez
1   Hospital del Mar, Gastroenterology, Barcelona, Spain
2   Hospital Del Mar Medical Research Institute, IMIM, Barcelona, Spain
,
MAP Sanchez
1   Hospital del Mar, Gastroenterology, Barcelona, Spain
,
BB Cabredo
3   Hospital Universitario de Burgos, Gastroenterology, Brugos, Spain
,
A García-Rodriguez
4   Hospital de Viladecans, Gastroenterology, Viladecans, Spain
,
SF Larramona
5   Hospital de Santa Bárbara, Gastroenterology, Soria, Spain
,
ON Rincón
6   Hospital Gregorio Marañón, Endoscopic Unit, Madrid, Spain
,
PD Redondo
7   Hospital Universitario Rio Hortega, Endoscopic Unit, Valladolid, Spain
,
I Puig del Castillo
8   Hospital de Manresa, Althaia, Gastroenterology, Manresa, Spain
,
C Romero Mascarell
9   Consorci Sanitari de Terrassa, Gastroenterology, Terrassa, Spain
,
IR Sánchez-Miguel
10   Hospital 12 de Octubre, Endoscopy Unit, Madrid, Spain
,
N Caballero
11   Hospital Universitari Germans Trias I Pujol, Endoscopy Unit, Badalona, Spain
,
I Ibañez
1   Hospital del Mar, Gastroenterology, Barcelona, Spain
,
D Hernández Negrín
12   Hospital Universitario de Canarias, Gastroenterology, Tenerife, Spain
,
GB Sadornil
13   Hospital Universitario de Burgos, Gastroenterology, Burgos, Spain
,
AP Oltra
4   Hospital de Viladecans, Gastroenterology, Viladecans, Spain
,
R Pérez Berbegal
1   Hospital del Mar, Gastroenterology, Barcelona, Spain
,
GC Urquiza
1   Hospital del Mar, Gastroenterology, Barcelona, Spain
,
AS Urgorri
1   Hospital del Mar, Gastroenterology, Barcelona, Spain
,
JA Martínez
14   Open University of Catalonia, Barcelona, Spain
,
AZ Gimeno-García
12   Hospital Universitario de Canarias, Gastroenterology, Tenerife, Spain
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

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Aims The most important predictor of unsuccessful bowel preparation (BP) is a previous failure. There are no standardized recommendations to prepare those patients.

The aim of this study was to analyse the efficacy in BP success of a nurse-led educational intervention by telephone within the 48 hours before the colonoscopy, in patients with previous BP failure.

Methods Multicentre randomized clinical trial with parallel groups (control and phone), endoscopist-blind. Consecutive patients with inadequate BP were included. A sample size of 652 participants was calculated to show a 10% improvement in BP success. Both groups received the same BP protocol including 4 liters PEG in split dose regimen. The main outcome was successful BP, defined as all colon segments with a Boston Bowel Preparation score with 2 or 3 points. No efficacy data were considered BP failures. Intention to treat (ITT) analysis included all randomized participants. Per protocol (PP) analysis included participants that could be contacted by telephone and control cases. Clinicaltrials identifier: NCT03055689

Results The investigators included, 651 consecutive participants in 11 hospitals.

ASA I score was more frequent in the control group, without other differences in the baseline characteristics. In the ITT analysis, comparing control and phone groups; BP success was 72% and 77.3%, absolute risk difference (ARD) 5.3%, (p=1.2). The attendance rate was 92% and 94% (p=0.25). In the phone group, 266 (83%) patients were contacted by telephone. Per protocol analysis showed a significant BP success increase, 83.5%, ARD 11.5 (p=0.001).

Conclusions This is the first multicenter randomized trial evaluating an educational intervention in patients with high risk of poor bowel preparation. A nurse-led telephone call did not reach a significant increase of BP success.However, when patients were effectively contacted and educated by phone, with an applicability of 83%, the bowel preparation success was significantly improved.