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DOI: 10.1055/s-0040-1704590
A REVIEW OF GROWTH AND INTERVENTION OF PANCREATIC CYSTIC LESIONS UNDER SURVEILLANCE IN A TERTIARY REFERRAL CENTRE
Publication History
Publication Date:
23 April 2020 (online)
Aims Our aim were to review our surveillance and intervention of pancreatic cystic lesions in our cohort from 2005–2019.
Methods Patients with pancreatic cystic lesions were identified from the records of the Upper GI oncology MDT in Tallaght Hospital. These patients clinical notes, radiology, and endoscopy records were all examined to determine progress of their disease. Death, surgery, or MDT discontinuation of surveillance at MDT were deemed the endpoints for our study.
Results 242 patients (139 female) were identified with pancreatic cystic lesions under surveillance in TUH. Median age of diagnosis was 69.
Mean cyst size at diagnosis was 19 mm (±14.5 mm); 81 patients had at least 1 worrisome feature at diagnosis.
24 patients progressed to surgery for their PCL while under surveillance, median time to surgery was five months, (range 1 month to 5 years). 16 patients had their surgery within a year of diagnosis. 14 patients died while still under surveillance, 14 further patients had their surveillance due to unsuitability for intervention.
The median length of follow up was 1.81 years (range 0.35–9.6 years). 84 patients underwent 6 month surveillance, mean size increased by 1.3 mm at 6 months. 108 patient received a 1 year scan, mean size decreased at one year by 0.41 mm. The mean annual cyst size change across our cohort surveillance (525.8 patient years) was 0.83 mm (±6.22 mm).
Conclusions The majority of our patient cohort who progressed to surgery had their operation within one year. The mean annual change was less than 1 mm making us question the benefit of annual surveillance of these patients beyond the first year of diagnosis.