Endoscopy 2020; 52(S 01): S208-S209
DOI: 10.1055/s-0040-1704650
ESGE Days 2020 ePoster Podium presentations
Thursday, April 23, 2020 15:00 – 15:30 Luminal EUS ePoster Podium 3
© Georg Thieme Verlag KG Stuttgart · New York

CLINICAL FACTORS THAT INFLUENCE THE ACCURACY OF ENDOSCOPIC ULTRASONOGRAPHY IN EARLY GASTRIC CANCER

S-J Kim
1   Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Division of Gastroenterology, Department of Internal Medicine, Seoul, Korea, Republic of
,
C-H Lim
2   Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Division of Gastroenterology, Department of Internal Medicine, Seoul, Korea, Republic of
,
HH Lee
1   Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Division of Gastroenterology, Department of Internal Medicine, Seoul, Korea, Republic of
,
YK Cho
1   Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Division of Gastroenterology, Department of Internal Medicine, Seoul, Korea, Republic of
,
B-I Lee
1   Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Division of Gastroenterology, Department of Internal Medicine, Seoul, Korea, Republic of
,
Y-S Cho
1   Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Division of Gastroenterology, Department of Internal Medicine, Seoul, Korea, Republic of
,
M-G Choi
1   Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Division of Gastroenterology, Department of Internal Medicine, Seoul, Korea, Republic of
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

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Aims Assessment of a tumor stage of early gastric cancer (EGC) is critical in its treatment modality. Endoscopic ultrasonography (EUS) has been used as a reliable method for staging the depth of invasion. However, its diagnostic accuracy is associated with a number of potential variables. This study is to investigate factors that influence accuracy of EUS for staging the depth of invasion in EGC.

Methods Patients with EGC who underwent surgical and/or endoscopic treatment were studied retrospectively. A pathological review was performed on all resected tissues. Factors such as tumor size, tumor location, pathologic results, and experience of endoscopists were analyzed.

Results A total of 223 EGCs from 211 patients (mean-age 62.8 years, 66.1% male) were included from March 2016 to September 2019 at an academic hospital (Seoul St. Mary’s hospital, Korea). The overall accuracy of EUS for staging the depth of invasion was 64.7%. The diagnostic accuracy of EUS for tumor invasion depth was significantly affected by the size of tumor, its location, and ulceration. The diagnostic accuracy for lesions either of 2-3cm or >3cm was significantly higher than for those ≤2cm respectively. (odds ratio: 3.15; 95% CI: 1.48-6.69, p=0.003; odds ratio: 4.70; 95% CI: 2.24-9.86, p< 0.001) The diagnostic accuracy for lesions located in lower one third of the stomach was also higher than those either in upper or mid one third of the stomach (odds ratio: 3.12; 95% CI: 1.01-9.60, p=0.047). Besides, ulceration showed significantly higher diagnostic accuracy (odds ratio: 3.11; 95% CI: 1.67-5.79, p< 0.001). However, diagnostic accuracy of EUS for staging the depth of invasion was not associated with patients’ pathologic results or experience of endoscopists.

Conclusions Our results suggest that the size of tumor, its location, and ulceration yielded a high accuracy of EUS, all of which should be cautiously considered in the decision on the treatment strategy.