Endoscopy 2020; 52(S 01): S271
DOI: 10.1055/s-0040-1704855
ESGE Days 2020 ePoster presentations
Thursday, April 23, 2020 09:00 – 17:00 Stomach and small intestine ePoster area
© Georg Thieme Verlag KG Stuttgart · New York

PREDICTING AN INAPPROPRIATE COLON CAPSULE CLEANSING: A STUDY APPROACHING PREDICTIVE FACTORS

R Magalhaes
1   Hospital Senhora da Oliveira, Guimarães, Portugal
2   Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
3   ICVS/3B’s, PT Government Associate Laboratory, Guimarães, Portugal
,
B Rosa
1   Hospital Senhora da Oliveira, Guimarães, Portugal
2   Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
3   ICVS/3B’s, PT Government Associate Laboratory, Guimarães, Portugal
,
MJ Moreira
1   Hospital Senhora da Oliveira, Guimarães, Portugal
2   Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
3   ICVS/3B’s, PT Government Associate Laboratory, Guimarães, Portugal
,
J Cotter
1   Hospital Senhora da Oliveira, Guimarães, Portugal
2   Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
3   ICVS/3B’s, PT Government Associate Laboratory, Guimarães, Portugal
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

Also available at
 

Aims An adequate colon cleansing is paramount to rely on colon capsule reported findings. To optimize the rate of adequate cleansing it may be important to identify risk factors that can predict a sub-optimal colon preparation. Being able to properly categorize the patients at major risk, will allow to select the subgroup in most need of enhanced cleansing protocols. We aim to define predictive factors for inappropriate bowel preparation in colon capsule.

Methods Retrospective, single center, cohort study. Patients’ demographics and data including endoscopic findings and quality of bowel preparation assessment were collected retrospectively from the medical records. A univariate analysis tested the association between covariables and the outcome, inappropriate cleansing. The statistically significant variables were included in multivariable logistic binary regression.

Results We included 83 consecutive colon capsules, from 2015 to 2019. Seventy-seven percent were female, with a mean age of 65 years. The main indication for initial colonoscopy was colorectal cancer screening (44%) followed by polyp surveillance (25,3%). The major reason for incomplete conventional colonoscopy was fixed angulation of the left colon (63%). Fifty percent of the colon capsules cleansing was graded as inappropriate. The variables colonic transit time, previous inappropriate preparation, impaired mobility, polimedication, chronic antidepressants, calcium channel blockers, chronic laxative drugs, obstipation and multiple comorbidities were statistically associated with an inappropriate cleansing (p < 0.05). The variables previous inappropriate cleansing (OR 8.3; p = 0.032), chronic laxative (OR 13; p=0.026) and chronic antidepressant medication (OR 12; p = 0.018), were independently associated with the outcome inappropriate cleansing.

Conclusions Previous inappropriate cleansing, chronic laxative and chronic antidepressant medication may increase the rate of inappropriate colon capsule cleansing up to 13-fold risk. These factors seem essential in the selection of patients for optimization of the colon cleansing protocol, aiming to diminish the rate of inappropriate colon capsule cleansing.