EPIDEMIOLOGY OF HELICOBACTER PYLORI FOR PATIENTS WITH GASTRIC DISEASES AND ASYMPTOMATIC POPULATION IN MOROCCO

Aims Helicobacter pylori infection is recognized as a worldwide problem, mainly in developing countries where infection reaches 80% of the population. H.pylori is associated with various gastric diseases, mainly, many benign, premalignant, and malignant lesions of the gastric mucosa. The aim of our study was to determine the prevalence of H.pylori infection in asymptomatic population and gastric disease’s patients.

Methods a total of 162 asymptomatic subjects collected from Casablanca blood transfusion, and 254 patients suffering from various gastric gastroenterology and oncology services of the Ibn Rochd University Hospital Center, were targeted lesions (chronic gastritis, atrophic gastritis, intestinal metaplasia, gastric cancer) collected from in this investigation. The typing of gastric lesions and H.pylori status were performed by Histological examination and ELISA test.

Results Our results showed a high prevalence of H. pylori infection in both populations Asymptomatic (92.6%) and gastric diseases patients: chronic gastritis (95%), atrophic gastritis (97%), intestinal metaplasia (100%) and gastric cancer (92%) . We noticed that the worsening of gastric lesions related to H.pylori infection increases with age, and it was influenced by tobacco consumption and the living area.

Conclusions It is necessary to update the recommendations regarding diagnosis, treatment of H. pylori infection, and follow-up of the patients, to avoid the evolution of simple chronic gastritis to gastric cancer.