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DOI: 10.1055/s-0040-1705044
USE OF NARROW BAND IMAGING COLONOSCOPY IN DIAGNOSIS OF ULCERATIVE COLITIS, CORRELATION WITH CONVENTIONAL COLONOSCOPY & HISTOPATHOLOGY
Publication History
Publication Date:
23 April 2020 (online)
Aims Ulcerative colitis is a disease of increasing incidence and may progress to colorectal cancer (CRC). Early detection of dysplastic changes is required. Narrow Band Imaging (NBI) is an imaging procedure that is supposed to increase the yielding of diagnosis of ulcerative colitis.
Aim of the study: Validate the relation between histological pattern and NBI findings in diagnosing ulcerative colitis.
Methods 50 patients diagnosed with ulcerative colitis in Alexandria University Hospital were examined by conventional white-light endoscopy (WLE) colonoscopy and NBI then biopsies were taken from areas with suspected lesions and histopathological examination was done.
Results patients were divided into active (27) and inactive (23) according to the Ulcerative colitis disease activity index (UCDAI). From the 23 patients that were supposed to be inactive, 14 showed honeycomb appearance and 7 showed irregular vascular mucosal patterns by NBI examination. Histopathological examination revealed metaplasia in 55% of the patients that were under the category of inactive patients. There was a significant correlation between histological examination and NBI findings. NBI showed sensitivity of 58.3%, specificity of 100%, PPV of 100%, NPV of 23% and accuracy of 62.9% in active patients.
Conclusions Narrow band imaging colonoscopy is an easy method that adds value for the conventional colonoscopic evaluation of the patients suffering from ulcerative colitis & seems to provide additional information that might lead to further classification of the endoscopic activity rather than the active or inactive.