Kerosene Poisoning Complicated by Acute Pancreatitis

Abstract

A 6-year-old male child patient was brought to the emergency pediatric room with alleged history of accidental ingestion of approximately 15 mL kerosene oil. The child developed vomiting shortly after the consumption. Chest radiograph taken 6 hours after ingestion did not show any abnormalities. On the second day of hospital stay, the patient started complaining of severe abdominal pain. His serum amylase and lipase levels were elevated significantly, suggesting the development of acute pancreatitis. He was investigated for the other possible causes of acute pancreatitis, which were normal. There is paucity of literature regarding occurrence of acute pancreatitis following kerosene poisoning, both in children, as well as adults, because of its rarity. A high index of suspicion should be kept in mind and a differential diagnosis of acute pancreatitis should be considered in cases of acute kerosene poisoning, who complain of pain in abdomen.

Keywords

acute pancreatitis - abdominal pain - children - kerosene - pediatric - poisoning

Authors' Contributions

S.S. and M.S.T. were involved in conceptualization of the manuscript, conducting literature search, and drafting the manuscript. S.S. and M.S.T. are both designated as first authors of this manuscript. Patient data were collected by S.S. and S.M. S.M. and M.A. helped in conducting literature search and revised the manuscript for scientific content. All the authors were involved in clinical management of the patient. M.S.T. will act as the guarantor for the paper.

Publikationsverlauf

Eingereicht: 03. Januar 2020

Angenommen: 31. Januar 2020

Artikel online veröffentlicht:
09. März 2020

• References

• 1 Shotar AM. Kerosene poisoning in childhood: a 6-year prospective study at the Princess Rahmat Teaching Hospital. Neuroendocrinol Lett 2005; 26 (06) 835-838
• 2 Dice WH, Ward G, Kelley J, Kilpatrick WR. Pulmonary toxicity following gastrointestinal ingestion of kerosene. Ann Emerg Med 1982; 11 (03) 138-142
• 3 Mahalakshmi R, Dinesh K, Naveed NM, Venkataraman P, Vinoth PN. Acute pancreatitis following kerosene ingestion- a rare association. Australas Med J 2013; 6: 382-383
• 4 Sunilkumar MN, Parvathy VK. Analysis of profile of childhood kerosene poisoning in a tertiary care medical college hospital. Int J Pediatr Res 2016; 3: 211-217
• 5 Dutta AK, Seth A, Goyal PK. et al. Poisoning in children: Indian scenario. Indian J Pediatr 1998; 65 (03) 365-370
• 6 Dayasiri MBKC, Jayamanne SF, Jayasinghe CY. Kerosene oil poisoning among children in rural Sri Lanka. Int J Pediatr 2017; 2017: 8798610
• 7 Kumaravel KS, Rameshbabu B. Kerosene poisoning in childhood: a 3-year retrospective study at a tertiary referral hospital. International Journal of Contemporary Medical Research 2016; 3: 1832-1834
• 8 Gupta P, Singh RP, Murali MV, Bhargava SK, Sharma P. Kerosene oil poisoning--a childhood menace. Indian Pediatr 1992; 29 (08) 979-984
• 9 Chilcott RP. Health Protection Agency. Compendium of chemical hazards: kerosene (fuel oil). Chemical Hazards and Poisons Division (HQ). Chilton, Didcot, Oxfordshire, OX11 0RQ, United Kingdom. Available at: https://www.who.int/ipcs/emergencies/kerosene.pdf . Accessed December 4, 2019
• 10 Sandilands D, Jeffrey IJM, Haboubi NY, MacLennan IAM, Braganza JM. Abnormal drug metabolism in chronic pancreatitis. Treatment with antioxidants. Gastroenterology 1990; 98 (03) 766-772
• 11 Murtaza G, Khalid MF, Mungo NA. Recurrent pantoprazole-associated pancreatitis. Am J Ther 2018; 25 (04) e492-e493