J Pediatr Intensive Care 2020; 09(04): 287-289
DOI: 10.1055/s-0040-1705184
Case Report

A 5-Month-Old Infant with Cardiorespiratory Arrest Caused by Food Protein-Induced Enterocolitis Syndrome to Cow's Milk Proteins

Martina Quattromani
1   Department of Pediatric Allergology, Regina Margherita Children's Hospital, Turin, Italy
,
Roberta Calzedda
1   Department of Pediatric Allergology, Regina Margherita Children's Hospital, Turin, Italy
,
Giovanna Monti
1   Department of Pediatric Allergology, Regina Margherita Children's Hospital, Turin, Italy
› Author Affiliations

Abstract

Food protein-induced enterocolitis syndrome (FPIES) is a nonimmunoglobulin E cell-mediated food allergy, which occurs predominantly in infants and young children. The most commonly incriminated triggers are cow's milk (CM), soy, and grains. Acute FPIES can be potentially life-threatening and culminate in shock requiring fluid resuscitation in at least 15% of the cases. To our knowledge, there have been no reports in literature of cardiorespiratory arrest induced by acute FPIES. We describe the first case of cardiorespiratory arrest occurred after accidental ingestion of a CM-based formula in a 5-month-old infant with previous diagnosis of FPIES to CM.



Publication History

Received: 28 November 2019

Accepted: 31 January 2020

Article published online:
06 March 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Stuttgart · New York

 
  • References

  • 1 Nowak-Węgrzyn A, Chehade M, Groetch ME. et al. International consensus guidelines for the diagnosis and management of food protein-induced enterocolitis syndrome: Executive Summary-Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol 2017; 139 (04) 1111-1126.e4
  • 2 Katz Y, Goldberg MR, Rajuan N, Cohen A, Leshno M. The prevalence and natural course of food protein-induced enterocolitis syndrome to cow's milk: a large-scale, prospective population-based study. J Allergy Clin Immunol 2011; 127 (03) 647-53.e1 , 3
  • 3 Barasche J, Stollar F, Bergmann MM, Caubet JC. Severely altered-consciousness status and profuse vomiting in infants: food protein-induced enterocolitis syndrome (FPIES), a challenging diagnosis. Pediatr Emerg Care 2018; 34 (10) e187-e189
  • 4 Chung HL, Hwang JB, Park JJ, Kim SG. Expression of transforming growth factor β1, transforming growth factor type I and II receptors, and TNF-α in the mucosa of the small intestine in infants with food protein-induced enterocolitis syndrome. J Allergy Clin Immunol 2002; 109 (01) 150-154
  • 5 Askari B, Ferreri NR. Regulation of prostacyclin synthesis by angiotensin II and TNF-alpha in vascular smooth muscle. Prostaglandins Other Lipid Mediat 2001; 63 (04) 175-187
  • 6 Miceli Sopo S, Battista A, Greco M, Monaco S. Ondansetron for food protein-induced enterocolitis syndrome. Int Arch Allergy Immunol 2014; 164 (02) 137-139
  • 7 Watts SW, Morrison SF, Davis RP, Barman SM. Serotonin and blood pressure regulation. Pharmacol Rev 2012; 64 (02) 359-388
  • 8 Koga H, Kobayashi H, Yamataka A, Lane GJ, Miyano T. Intercellular adhesion molecule (ICAM-1) response after major neonatal surgery. Pediatr Surg Int 2005; 21 (09) 695-700
  • 9 Kimura M, Ito Y, Tokunaga F. et al. Increased C-reactive protein and fever in Japanese infants with food protein-induced enterocolitis syndrome. Pediatr Int (Roma) 2016; 58 (09) 826-830