Neurological Nuance: Sporadic Burkitt's Lymphoma Presenting with Guillain–Barre Syndrome

Nadia Bouattour; Fatma Kamoun; Slim Charfi; Siham Ben Nsir; Wafa Bouchaala; Tahya Boudawara; Chahnez Triki

doi:10.1055/s-0040-1710515

Journal of Pediatric Neurology, Table of Contents

Journal of Pediatric Neurology 2021; 19(01): 054-058
DOI: 10.1055/s-0040-1710515

Case Report

Neurological Nuance: Sporadic Burkitt's Lymphoma Presenting with Guillain–Barre Syndrome

Nadia Bouattour

¹Department of Child Neurology, Hedi Chaker Hospital, Sfax, Tunisia

,

Fatma Kamoun

¹Department of Child Neurology, Hedi Chaker Hospital, Sfax, Tunisia

²Research Laboratory “Neuropediatrics,” University of Sfax, Sfax, Tunisia

,

Slim Charfi

³Department of Pathology, Habib Bourguiba Hospital, Sfax, Tunisia

,

Siham Ben Nsir

¹Department of Child Neurology, Hedi Chaker Hospital, Sfax, Tunisia

²Research Laboratory “Neuropediatrics,” University of Sfax, Sfax, Tunisia

,

Wafa Bouchaala

¹Department of Child Neurology, Hedi Chaker Hospital, Sfax, Tunisia

²Research Laboratory “Neuropediatrics,” University of Sfax, Sfax, Tunisia

,

Tahya Boudawara

³Department of Pathology, Habib Bourguiba Hospital, Sfax, Tunisia

,

Chahnez Triki

¹Department of Child Neurology, Hedi Chaker Hospital, Sfax, Tunisia

²Research Laboratory “Neuropediatrics,” University of Sfax, Sfax, Tunisia

› Author Affiliations

Abstract

Burkitt's lymphoma (BL) is a high-grade mature B cell neoplasm. Primary lymphoma of the central nervous system (CNS) is very rare. In contrast, BL can be localized in any part of the body and may spread to the CNS. Peripheral nervous system impairment caused by BL has been thoroughly described. However, Guillain–Barre syndrome (GBS) does not commonly appear as an initial manifestation of BL. We presented the case of a young child with sporadic BL with neuromeningeal involvement and spinal cord compression whose first clinical manifestation was the appearance of GBS. Lymphoma should be taken into account, especially in children presenting with the clinical features of acute polyradiculoneuropathy.

Keywords

Guillain–Barre's syndrome - Burkitt's lymphoma - lymphoma - neurology

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References

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