New indications for use of bioactive glass (S53P4) in middle ear surgery

In the last couple of years S53P4 (BonAlive®) has established as material for obliteration of radical cavities.

At ENT department in Halberstadt S53P4 has been used in more than 180 cases. The initial focus was on obliteration of open mastoid cavities and in combination with VSB- or Cochlear Implantation. Meanwhile, S53P4 is also used in chronic mastoiditis and in cholesteatoma surgery in CWU technique.

Since 2018 a total number of 15 operations have been performed in these cases. In 8 patients the obliteration was carried out as part of CWU-cholesteatoma surgery, 4 patients underwent obliteration due to chronic mastoiditis and 1 patient was obliterated bilaterally in case of granular mastoiditis concerning mantle cell lymphoma.

The average follow up-time is 6 months.

For 3 patients after cholesteatoma surgery follow up-results are available. There is no evidence for recurrent cholesteatoma, the tympanic membrane is intact in all 3 cases, there is no epitympanal retraction visible.

3 of 4 patients who received an obliteration in chronic mastoiditis are symptom-free. One patient received a T-Tube because of recurrent effusion. In this case a complete traumatic closure of the epipharyngeal tube ostium is present.

The patient with mantle cell lymphoma is under regular surveillance. Currently no further operations are planned.

Due to its antibacterial properties, S53P4 is suitable as alloplastic material in middle ear surgery. When used properly, atelectasis of the tympanic membrane can be prevented. Further investigations are indicated.

Poster-PDF A-1246.PDF

Publication History

Article published online:
10 June 2020