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CC BY 4.0 · TH Open 2020; 04(03): e175-e177
DOI: 10.1055/s-0040-1715791
Case Report

COVID-19 and Cold Agglutinin Hemolytic Anemia

Diana V. Maslov 
1   Department of Internal Medicine, Ochsner Clinic Foundation, New Orleans, Louisiana, United States
,
Victoria Simenson
1   Department of Internal Medicine, Ochsner Clinic Foundation, New Orleans, Louisiana, United States
,
Suma Jain
2   Department of Pulmonary and Critical Care, Ochsner Clinic Foundation, New Orleans, Louisiana, United States
,
Ambuga Badari
3   Department of Haematology and Oncology, Ochsner Clinic Foundation, New Orleans, Louisiana, United States
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Abstract

Novel coronavirus disease 2019 (COVID-19) has spread throughout the world and has infected close to 4 million people. It commonly presents with fever, cough, and fatigue. Due to the high inflammatory response, it is suggested that the coagulation cascade is enhanced causing thrombotic events for many patients. We describe a patient with clinical features of cerebrovascular accident, as well as documented blood clots in bilateral upper extremities. Labs revealed the presence of cold agglutinin hemolytic anemia. The association between cold agglutinin autoimmune hemolytic anemia and thrombotic events in COVID-19 patients has not been well investigated. The patient unfortunately passed away within 48 hours after admission. This case stresses the importance of considering a full workup to diagnose autoimmune hemolytic anemia (AIHA) in COVID-19 patients with thromboses and possible implications for management.

Keywords

viral infection - thrombosis - autoantibodies


Publikationsverlauf

Eingereicht: 02. Juni 2020

Angenommen: 17. Juli 2020

Artikel online veröffentlicht:
20. August 2020

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).

Georg Thieme Verlag KG
Stuttgart · New York

 

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