Anwendung von Hydroxyethylstärke (HES) bei Hund und Katze – eine Übersicht

Katja-Nicole Adamik; Muriel Christen

doi:10.1055/s-0041-110687

kleintier konkret, Table of Contents

kleintier konkret 2016; 19(02): 17-22
DOI: 10.1055/s-0041-110687

hund|katze

intensivmedizin

Enke Verlag in Georg Thieme Verlag KG Stuttgart

Anwendung von Hydroxyethylstärke (HES) bei Hund und Katze – eine Übersicht

Authors

Katja-Nicole Adamik

¹Dipl. ACVECC, Dipl. ECVECC, Emergency and Critical Care, Universität Bern, Vetsuisse-Fakultät Departement für klinische Veterinärmedizin
Muriel Christen

²cand. med. vet.

Abstract

All articles of this category

Die Wirksamkeit und Sicherheit von HES werden in der Humanmedizin kontrovers diskutiert. Dieser Artikel gibt eine Übersicht über die Anwendung beim Kleintier, dabei werden die physiologischen Grundlagen des Wirkprinzips im Zusammenspiel mit der Blutgefäßbarriere, die Effekte und Indikationen sowie die Nebenwirkungen des Präparats erläutert.

Full Text

References

Literatur
1 Aarnes TK, Bednarski RM, Lerche P et al. Effect of intravenous administration of lactated Ringer’s solution or hetastarch for the treatment of isoflurane-induced hypotension in dogs. Am J Vet Res 2009; 70 (11): 1345-1353
2 Adamik KN, Yozova ID, Regenscheit N. Controversies in the use of hydroxyethyl starch solutions in small animal emergency and critical care. J Vet Emerg Crit Care 2015; 25 (1): 20-47
3 Barros JM, do Nascimento P Jr., Marinello JL et al. The effects of 6 % hydroxyethyl starch-hypertonic saline in resuscitation of dogs with hemorrhagic shock. Anesth Analg 2011; 112 (2): 395-404
4 Bednarski R, Grimm K, Harvey R et al. AAHA anesthesia guidelines for dogs and cats. J Am Anim Hosp Assoc 2011; 47 (6): 377-385
5 Boscan P, Pypendop BH, Siao KT et al. Fluid balance, glomerular filtration rate, and urine output in dogs anesthetized for an orthopedic surgical procedure. Am J Vet Res 2010; 71 (5): 501-507
6 Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM). Medizinprodukte BfArM. Anwendungsbeschränkung für HES-haltige Arzneimittel 2013 [12.11.2013] Im Internet: http://www.bfarm.de/SharedDocs/Risikoinformationen/Pharmakovigilanz/DE/RHB/2013/rhb-hes.pdf?__blob=publicationFile&v=6 Stand: März 2016
7 Cortellini S, Pelligand L, Syme H et al. Evaluation of serial plasma and urine neutrophil gelatinase-associated lipocalin (N-gal) in dogs with SIRS undergoing emergency laparotomy (Abstr). J Vet Emerg Crit Care 2014; 24 (S1) S29
8 Finfer S, Liu B, Taylor C et al. Resuscitation fluid use in critically ill adults: an international cross-sectional study in 391 intensive care units. Crit care 2010; 14 (5) R185
9 Gauthier V, Holowaychuk MK, Kerr CL et al. Effect of synthetic colloid administration on hemodynamic and laboratory variables in healthy dogs and dogs with systemic inflammation. J Vet Emerg Crit Care 2014; 24 (3): 251-258
10 Hayes G, Benedicenti L, Mathews K. Retrospective cohort study on the incidence of acute kidney injury and death following hydroxyethyl starch (HES 10 % 250/0.5/5:1) administration in dogs (2007–2010). J Vet Emerg Crit Care 2016; 26 (1): 35-40
11 Jacob M, Chappell D, Hofmann-Kiefer K et al. The intravascular volume effect of Ringer’s lactate is below 20 %: a prospective study in humans. Crit Care 2012; 16 (3) R86
12 Jacob M, Chappell D, Hofmann-Kiefer K et al. [Determinants of insensible fluid loss. Perspiration, protein shift and endothelial glycocalyx] Anaesthesist 2007; 56 (8): 747-758 760–764
13 Kozek-Langenecker SA. Effects of hydroxyethyl starch solutions on hemostasis. Anesthesiology 2005; 103 (3): 654-660
14 Mazzaferro E, Rudloff E, Kirby R. The role of albumin replacement in the critically ill veterinary patient. J Vet Emerg Crit Care 2002; 12 (2): 113-124
15 Myburgh JA, Finfer S, Bellomo R et al. Hydroxyethyl starch or saline for fluid resuscitation in intensive care. N Eng J Med 2012; 367 (20): 1901-1911
16 Pascoes P. Perioperative management of fluid therapy. In: DiBartola S, ed. Fluid, Electrolyte, and Acid-Base Disorders in Small Animal Practice. 4^th ed. St. Louis, Missouri: Saunders; 2012
17 Perner A, Haase N, Guttormsen AB et al. Hydroxyethyl starch 130/0.42 versus Ringer’s acetate in severe sepsis. N Eng J Med 2012; 367 (2): 124-134
18 Rehm M, Zahler S, Lötsch M et al. Endothelial glycocalyx as an additional barrier determining extravasation of 6 % hydroxyethyl starch or 5 % albumin solutions in the coronary vascular bed. Anesthesiology 2004; 100 (5): 1211-1223
19 Rudloff E, Kirby R. Colloid fluid therapy. In: Bonagura JD, Twedt DC, eds. Kirk’s Current Veterinary Therapy XV. 15^th ed. St. Louis, Missouri: Elsevier Saunders; 2014: 8-14
20 Rudloff E, Kirby R. Fluid resuscitation and the trauma patient. Vet Clin North Am Small Anim Pract 2008; 38 (3): 645-652
21 Schortgen F, Brochard L. Colloid-induced kidney injury: experimental evidence may help to understand mechanisms. Critical Care 2009; 13 (2): 130
22 Smiley LE. The use of hetastarch for plasma expansion. Probl Vet Med 1992; 4 (4): 652-667
23 Smiley LE, Garvey MS. The use of hetastarch as adjunct therapy in 26 dogs with hypo-albuminemia: a phase two clinical trial. J Vet Intern Med 1994; 8 (3): 195-202
24 Westphal M, James MF, Kozek-Langenecker S et al. Hydroxyethyl starches: different products – different effects. Anesthesiology 2009; 111 (1): 187-202
25 Wiedermann CJ, Joannidis M. Accumulation of hydroxyethyl starch in human and animal tissues: a systematic review. Intensive Care Med 2014; 40 (2): 160-170
26 Yozova ID, Howard J, Adamik K-N. Effects of a waxy maize-derived 6 % tetrastarch (hydroxyethyl starch 130/0.4) on plasma creatinine levels in dogs – a retrospective analysis (2010–2013) (Abstr). J Vet Emerg Crit Care 2014; 24 (S1) S31