Eur J Pediatr Surg
DOI: 10.1055/s-0041-1723993
Original Article

Hypospadias and the Use of the Ages and Stages Questionnaire to Evaluate Neurodevelopmental Status of Boys with Hypospadias

Murat Cakmak
1  Department of Pediatric Surgery, Ankara University School of Medicine, Ankara, Turkey
,
Gulnur Gollu
1  Department of Pediatric Surgery, Ankara University School of Medicine, Ankara, Turkey
,
Ufuk Ates
1  Department of Pediatric Surgery, Ankara University School of Medicine, Ankara, Turkey
,
Ergun Ergun
1  Department of Pediatric Surgery, Ankara University School of Medicine, Ankara, Turkey
,
Ferid Khanmammadov
1  Department of Pediatric Surgery, Ankara University School of Medicine, Ankara, Turkey
,
Sumeyye Sozduyar
1  Department of Pediatric Surgery, Ankara University School of Medicine, Ankara, Turkey
,
Onur Telli
2  Department of Pediatric Urology, Kartal Dr. Lutfi Kirdar Training and Research Hospital, Istanbul, Turkey
,
Kenan Kose
3  Department of Biostatistics, Ankara University School of Medicine, Ankara, Turkey
,
Habibe Dilsiz
1  Department of Pediatric Surgery, Ankara University School of Medicine, Ankara, Turkey
,
Aytul Cakmak
4  Department of Public Health, Ufuk Univercity School of Medicine, Ankara, Turkey
5  Department of Child and Adolescent Psychiatry, Ankara University School of Medicine, Ankara, Turkey
,
Emine G. Kapci
5  Department of Child and Adolescent Psychiatry, Ankara University School of Medicine, Ankara, Turkey
,
Sevgi Kucuker
5  Department of Child and Adolescent Psychiatry, Ankara University School of Medicine, Ankara, Turkey
,
Ozgur Oner
5  Department of Child and Adolescent Psychiatry, Ankara University School of Medicine, Ankara, Turkey
,
Meltem Bingol-Kologlu
1  Department of Pediatric Surgery, Ankara University School of Medicine, Ankara, Turkey
,
Aydin Yagmurlu
1  Department of Pediatric Surgery, Ankara University School of Medicine, Ankara, Turkey
5  Department of Child and Adolescent Psychiatry, Ankara University School of Medicine, Ankara, Turkey
,
Rana I. Uslu
5  Department of Child and Adolescent Psychiatry, Ankara University School of Medicine, Ankara, Turkey
› Author Affiliations
Funding None.

Abstract

Introduction Placental insufficiency is one of the reasons for the reduction of hormone production. Thus, if one of the suspected causes of hypospadias is placental insufficiency, then the neurodevelopmental status of boys with hypospadias may be impaired. The aim of this study was to evaluate the neurodevelopmental status of boys with hypospadias and guide the parents of those who need support to related departments for early intervention.

Materials and Methods Boys were divided into two groups, those with hypospadias (group H) and healthy children undergoing traditional circumcision (group C). The parents of the boys completed the Ages and Stages Questionnaire (ASQ) and ASQ–Social Emotional (SE), both of which are screening instruments for the early identification of developmental and social–emotional problems, respectively.

Results Seventy-eight boys had hypospadias and 59 were admitted for traditional circumcision. The group H had statistically significant more impaired scores than group C in communication, gross motor, and personal–social skill sections. The multivariate logistic regression analysis revealed that hypospadias was the independent predictive factor for communication and personal–social skills.

Conclusion Hypospadias and neurologic impairment may share common etiologic factors. Accordingly, physicians should keep in mind that if a boy presents with hypospadias, the possibility of having neurologic impairment is higher than normal population and early intervention has crucial importance. Every boy with hypospadias should be evaluated for neurodevelopmental status.

Ethic Approval

Ethics committee approval was provided for the study. Written informed consent was obtained from the legal guardians of each child




Publication History

Received: 31 October 2020

Accepted: 04 January 2021

Publication Date:
04 March 2021 (online)

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