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CC BY 4.0 · Journal of Child Science 2021; 11(01): e74-e79
DOI: 10.1055/s-0041-1726460
Original Article

Delayed Cord Clamping in Infants of Diabetic Mothers: Laboratory and Clinical Outcomes

Shaimaa Reda Abdelmaksoud 
1   Department of Pediatrics, Benha Faculty of Medicine, Benha University, Benha, Egypt
,
Heba Elsayed Abdelraziq
2   Department of Obstetrics and Gynecology Benha Faculty of Medicine, Benha University, Benha, Egypt
,
Rana Atef khashaba 
3   Department of Clinical Pathology and Chemistry, Benha Faculty of Medicine, Benha University, Benha, Egypt
,
Aliaa Mohamed Diab
1   Department of Pediatrics, Benha Faculty of Medicine, Benha University, Benha, Egypt
› Author Affiliations Funding None.
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Abstract

The aim of this study was to compare the effects of delayed cord clamping (DCC) and early cord clamping (ECC) on venous hematocrit (htc) and clinical outcomes in infants of diabetic mothers (IDMs). This prospective randomized study included 157 term IDMs. The umbilical cords of these infants were clamped at least 60 seconds in group I (DCC group, n = 79) and as soon as possible after birth in group II (ECC group, n = 78). The two groups were compared regarding neonatal venous htc levels, hypoglycemia rates, jaundice requiring phototherapy, respiratory distress, and admission to the neonatal intensive care unit (NICU). Hematocrit levels were significantly higher in the DCC group, both at 6 and 24 hours postnatally (p = 0.039 and 0.01), respectively. Polycythemia frequency was higher in DCC than the ECC group, but no patient in either group needed partial exchange transfusion (PET). Rates of jaundice were significantly higher in the DCC group (p = 0.028), but there was no significant difference between the two groups regarding jaundice requiring phototherapy (p = 0.681). There were no differences between the groups regarding hypoglycemia rates, need for glucose infusion, or respiratory distress. The incidence of admission to NICU was lower in the DCC group (p = 0.005). Early clamping was a significant predictor for increased risk of NICU admission. DCC increased polycythemia and jaundice rates but did not increase the need for PET or phototherapy. Also, DCC reduced the severity of respiratory distress and the subsequent need for NICU admission.

Keywords

delayed cord clamping - infants of diabetic mothers - polycythemia


Publication History

Received: 08 December 2020

Accepted: 18 February 2021

Article published online:
01 April 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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